Epidemiological, anatomopathological, and immunophenotypical aspects of cutaneous lymphomas in dogs

Página do item simplificado
dc.contributor.authorMazaro, Renata D.
dc.contributor.authorLorenzetti, Douglas M.
dc.contributor.authorLeite, Suzana M.G.
dc.contributor.authorMasuda, Eduardo K.
dc.contributor.authorDa Costa, Leonardo D.
dc.contributor.authorVasconcelos, Rosemeri O. [UNESP]
dc.contributor.authorDantas, Antonio Flávio M.
dc.contributor.authorLacerda, Luciana C.
dc.contributor.authorDa Silva, Tereza Cristina
dc.contributor.authorMotta, Marco Aurélio A.
dc.contributor.authorCogliati, Bruno
dc.contributor.authorFighera, Rafael A.
dc.contributor.institutionUniversidade Federal de Sergipe (UFS)
dc.contributor.institutionVeterinarian
dc.contributor.institutionAxys Análises – Diagnóstico Veterinário e Consultoria Ltda.
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade Federal de Campina Grande (UFCG)
dc.contributor.institutionCélula – Laboratório Veterinário
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionCentro Clínico e Cirúrgico Veterinário (CCCV)
dc.date.accessioned2023-07-29T13:49:52Z
dc.date.available2023-07-29T13:49:52Z
dc.date.issued2023-01-01
dc.description.abstractCutaneous lymphomas are uncommon tumors in dogs that can occur as epitheliotropic and non-epitheliotropic types. The epitheliotropic type comprises three, already well established, distinct clinicopathological presentations. However, the non-epitheliotropic lymphoma, despite its poor characterization, represents a heterogeneous group of not yet correlated presentations that can mimic different skin tumors, configuring a diagnostic challenge. Therefore, this study’s main aim was to establish whether there is a correlation between the macroscopic presentation and the histological subtypes of cutaneous non-epitheliotropic lymphoma in the population of dogs involved in this study. Additionally, we aimed to determine the prevalence of each type and histological subtype of canine cutaneous lymphoma and describe the epidemiological and anatomopathological characteristics of the presented cases. From a total of 38 cases of cutaneous lymphoma diagnosed in dogs, 17 (44.7%) were considered as epitheliotropic and 21 (55.3%) as non-epitheliotropic. From the 17 cases of cutaneous epitheliotropic lymphoma, 13 (34.2%) and four (10.5%) were subclassified as mycosis fungoides and pagetoid reticulosis, respectively. The cases of cutaneous non-epitheliotropic lymphoma included were: anaplastic large T-cell lymphoma (ALTCL – 9/21, 23.9%), peripheral T-cell lymphoma, unspecified (PTCL-NOS – 4/21, 10.5%), subcutaneous panniculitis-like T-cell lymphoma (SPTCL – 4/21, 10.5%), diffuse large B-cell lymphoma – immunoblastic type (DLBCL – 2/21, 5.2%), lymphomatoid granulomatosis (LYG – 1/21, 2.6%), and marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT) - lymphoplasmacytic variant (1/21, 2.6%). Based on the anatomopathological findings, it was possible to infer that when faced with multiple, nodular or placoid skin lesions, predominantly on the trunk and limbs, the diagnosis is more likely to be consistent with ALTCL. Whereas, with solitary skin nodules or plaques, PTCL-NOS will be the most frequently observed histological type. When these lesions are exclusively located in the subcutaneous tissue, one should first think about SPTCL and, more rarely, DLBCL. Regarding to epitheliotropic cutaneous lymphomas, the most commonly observed type in dogs is the cutaneous form of mycosis fungoides, especially in the pre-mycotic and mycotic phases. We hope that this information can assist veterinary clinicians and pathologists in their diagnostic routines and contribute to the characterization of non-epitheliotropic cutaneous lymphomas in the canine species.en
dc.description.affiliationPrograma de Pós-graduação em Medicina Veterinária área de concentração em Patologia e Patologia Clínica Veterinária Centro de Ciências Rurais (CCR) Universidade Federal de Santa Maria (UFSM), Av. Roraima 1000, Camobi, RS
dc.description.affiliationVeterinarian, Rua Conde de Irajá 420, Botafogo
dc.description.affiliationAxys Análises – Diagnóstico Veterinário e Consultoria Ltda., Rua Alberto Silva 332, Vila Ipiranga
dc.description.affiliationVeterinarian, Rua Bolívia 575, São Pedro
dc.description.affiliationLaboratório de Histopatologia Veterinária (LHV) Faculdade de Ciências Agrárias e Veterinárias Departamento de Patologia Reprodução e Saúde Única Universidade Estadual Paulista “Júlio de Mesquita Filho” (Unesp), Via de Acesso Prof. Paulo Donato s/n
dc.description.affiliationLaboratório de Patologia Animal (LPA) Hospital Veterinário Universitário Centro de Saúde e Tecnologia Rural (CSTR) Universidade Federal de Campina Grande (UFCG), Av. Universitária s/n, Santa Cecília
dc.description.affiliationCélula – Laboratório Veterinário, Rua Castro Alves 398, Centro
dc.description.affiliationLaboratório de Patologia Morfológica e Molecular (LAPMOL) Faculdade de Medicina Veterinária e Zootecnia (FMVZ) Universidade de São Paulo (USP) Cidade Universitária, Avenida Prof. Dr. Orlando Marques de Paiva 87
dc.description.affiliationCentro Clínico e Cirúrgico Veterinário (CCCV), Rua Gonçalves Chaves 4806, Centro
dc.description.affiliationDepartamento de Patologia Centro de Ciências da Saúde Universidade Federal de Santa Maria (UFSM), Av. Roraima 1000, Camobi
dc.description.affiliationUnespLaboratório de Histopatologia Veterinária (LHV) Faculdade de Ciências Agrárias e Veterinárias Departamento de Patologia Reprodução e Saúde Única Universidade Estadual Paulista “Júlio de Mesquita Filho” (Unesp), Via de Acesso Prof. Paulo Donato s/n
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.identifierhttp://dx.doi.org/10.1590/1678-5150-PVB-7124
dc.identifier.citationPesquisa Veterinaria Brasileira, v. 43.
dc.identifier.doi10.1590/1678-5150-PVB-7124
dc.identifier.issn1678-5150
dc.identifier.issn0100-736X
dc.identifier.scopus2-s2.0-85151821840
dc.identifier.urihttp://hdl.handle.net/11449/248649
dc.language.isoeng
dc.relation.ispartofPesquisa Veterinaria Brasileira
dc.sourceScopus
dc.subjectcutaneous tumors
dc.subjectdermatopathology
dc.subjectdogs
dc.subjectSkin lymphomas
dc.subjectuncommon lymphomas
dc.titleEpidemiological, anatomopathological, and immunophenotypical aspects of cutaneous lymphomas in dogsen
dc.typeArtigo
unesp.departmentPatologia Veterinária - FCAVpt

Arquivos

Coleções

Jaboticabal - FCAV - Faculdade de Ciências Agrárias e Veterinárias