Lepromatous leprosy with dermatofibroma features: colonization or morphological variant of histoid leprosy with epidermal induction?

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dc.contributor.authorOuti Pontes, Cinthia Maria
dc.contributor.authorLourenco Pontes, Alexandre Lizardo
dc.contributor.authorOcanha-Xavier, Juliana Polizel [UNESP]
dc.contributor.authorXavier-Júnior, José Cândido Caldeira [UNESP]
dc.contributor.institutionPrivate Clinic
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionCentro Universitário Católico Unisalesiano Auxilium
dc.contributor.institutionPathology Institute of Araçatuba
dc.date.accessioned2022-04-29T08:46:46Z
dc.date.available2022-04-29T08:46:46Z
dc.date.issued2022-01-01
dc.description.abstractBackground: Leprosy is one of the main health problems in developing countries. It can show many different clinical presentations. Case report: A 37-yr-old woman with multiple reddish-brown papules on the lower and upper limbs, including the palms. The initial clinical impression was pityriasis lichenoides chronica. Biopsies were taken. The specimen from the left shin showed classical histological features of lepromatous leprosy. The specimen from the left thigh was similar to lipidized dermatofibroma showing epidermal hyperplasia with basal layer hyperpigmentation, a narrow Grenz zone, and spindle xanthomatous cells among dermal fibers. Fite-Faraco staining revealed many bacilli. Discussion: No matter the clinical presentation, in the presence of lipidized macrophages, Fite-Faraco staining (an inexpensive method available worldwide) should be performed to rule out leprosy, even in nonendemic areas or associated with a tumor.en
dc.description.affiliationPrivate Clinic
dc.description.affiliationSchool of Medicine Botucatu Medical School Paulista State University (UNESP), Botucatu
dc.description.affiliationSchool of Medicine Centro Universitário Católico Unisalesiano Auxilium, Araçatuba
dc.description.affiliationPathology Institute of Araçatuba
dc.description.affiliationUnespSchool of Medicine Botucatu Medical School Paulista State University (UNESP), Botucatu
dc.identifierhttp://dx.doi.org/10.1111/ijd.16172
dc.identifier.citationInternational Journal of Dermatology.
dc.identifier.doi10.1111/ijd.16172
dc.identifier.issn1365-4632
dc.identifier.issn0011-9059
dc.identifier.scopus2-s2.0-85127317802
dc.identifier.urihttp://hdl.handle.net/11449/231643
dc.language.isoeng
dc.relation.ispartofInternational Journal of Dermatology
dc.sourceScopus
dc.titleLepromatous leprosy with dermatofibroma features: colonization or morphological variant of histoid leprosy with epidermal induction?en
dc.typeArtigo
unesp.author.orcid0000-0002-1200-3730[3]
unesp.author.orcid0000-0003-0503-419X[4]

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