Green chromatographic fingerprinting: An environmentally friendly approach for the development of separation methods for fingerprinting complex matrices

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dc.contributor.authorFunari, Cristiano Soleo [UNESP]
dc.contributor.authorCarneiro, Renato Lajarim
dc.contributor.authorAndrade, Andre Marques [UNESP]
dc.contributor.authorHilder, Emily Frances
dc.contributor.authorCavalheiro, Alberto José [UNESP]
dc.contributor.institutionUniv Tasmania
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.date.accessioned2014-12-03T13:08:40Z
dc.date.available2014-12-03T13:08:40Z
dc.date.issued2014-01-01
dc.description.abstractA chromatographic fingerprint is a comprehensive method that reveals the distinctive pattern of peaks across the chromatogram for a given sample. It is considered an effective strategy to assess the identity and quality of herbal materials, as well as for the control of the quality of their derived products. HPLC is the most employed technique for these purposes and it is used routinely for quality control in industry. Hence, its impact on the environment should not be neglected. This work provides a rational and generic procedure to qualitatively fingerprint complex matrices. Resource- and time-saving experimental designs were selected; an alternative safer organic solvent was tested and a time-saving and innovative response entitled the green chromatographic fingerprinting response was developed and employed. This procedure was applied in the development of chromatographic fingerprints for extracts of Bauhinia forficata and Casearia sylvestris. Moreover, the response proposed here can be combined with a complementary metric available in the literature to compare methods using different solvents. According to this, the chromatographic fingerprints developed here using ethanol as the organic solvent provided a performance better than that of reference methods in which more harmful acetonitrile or methanol were employed.en
dc.description.affiliationUniv Tasmania, Australian Ctr Res Separat Sci ACROSS, Sch Chem, Hobart, Tas 7001, Australia
dc.description.affiliationSao Paulo State Univ, Inst Chem, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Carlos, Dept Chem, BR-13560 Sao Carlos, SP, Brazil
dc.description.affiliationUnespSao Paulo State Univ, Inst Chem, Sao Paulo, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipAustralian Research Council
dc.description.sponsorshipIdFAPESP: 10/16520-5
dc.description.sponsorshipIdFAPESP: 12/15844-7
dc.format.extent37-44
dc.identifierhttp://dx.doi.org/10.1002/jssc.201300955
dc.identifier.citationJournal Of Separation Science. Weinheim: Wiley-v C H Verlag Gmbh, v. 37, n. 1-2, p. 37-44, 2014.
dc.identifier.doi10.1002/jssc.201300955
dc.identifier.issn1615-9306
dc.identifier.lattes2518006820764120
dc.identifier.urihttp://hdl.handle.net/11449/111459
dc.identifier.wosWOS:000329478100007
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofJournal of Separation Science
dc.relation.ispartofjcr2.415
dc.relation.ispartofsjr0,795
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectBauhinia forficataen
dc.subjectCasearia sylvestrisen
dc.subjectQuality by designen
dc.subjectGreen liquid chromatographyen
dc.subjectMetabolite profilingen
dc.titleGreen chromatographic fingerprinting: An environmentally friendly approach for the development of separation methods for fingerprinting complex matricesen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderWiley-Blackwell
unesp.author.lattes2518006820764120[5]
unesp.author.orcid0000-0001-8214-9957[5]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Química, Araraquarapt

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Artigos - Química Orgânica - IQ