Recanalization Rates after Acute Deep Vein Thrombosis: A Single-center Experience Using a Newly Proposed Vein Diameter Variation Index

Página do item simplificado
dc.contributor.authorBrandao, Gustavo M. S. [UNESP]
dc.contributor.authorSobreira, Marcone Lima [UNESP]
dc.contributor.authorMalgor, Rafael D.
dc.contributor.authorRollo, Hamilton Almeida [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionSUNY Stony Brook
dc.date.accessioned2015-03-18T15:53:19Z
dc.date.available2015-03-18T15:53:19Z
dc.date.issued2014-10-01
dc.description.abstractBackground: Duplex ultrasound scanning (DUS) is the method of choice for diagnosis of deep vein thrombosis (DVT). However, only a few studies have performed prospective serial DUS after an acute episode of DVT to assess its evolution. This study aimed to report our experience using DUS combined with a thrombosis score (TS) and a newly proposed vein diameter variation index (VDVI) to evaluate the rate of resolution of DVT by assessing and quantifying the early stages of vein recanalization in proximal vein segments within 6 months after an episode of acute lower extremity DVT.Methods: Twelve patients with first episode of acute lower extremity DVT confirmed by DUS as occurring in <= 10 days after the onset of venous thrombosis symptoms were followed up prospectively for 6 months. TS and VDVI were calculated at 1, 3, and 6 months to assess vein recanalization. Intra-thrombus arteriovenous fistula formation was also investigated and related to the recanalization process.Results: Seven (58%) women were included, with a total cohort median age of 53.5 +/- 19 years. The left lower extremity was affected in 7 (58%) patients. DVT was diagnosed in 55 proximal vein segments. All patients had proximal DVT, with involvement of the external iliac, femoral, and popliteal veins. After 6 months, there was a significant decrease in TS and increase in VDVI (P < 0.001) in all proximal vein segments assessed, indicating thrombus regression. The more distal the DVT was, the faster was the VDVI increase, with most popliteal veins being recanalized at 3 months (P < 0.001). Intra-thrombus arteriovenous fistula was identified in 50% of patients at 1 month while on anticoagulation.Conclusions: The combined use of two different DUS-based assessment tools, TS and the proposed VDVI, provided an effective method to prospectively assess vein recanalization rates after an episode of acute lower extremity DVT in this series of patients and may allow a correct evaluation of DVT and its resolution or progression.en
dc.description.affiliationUniv Estadual Paulista UNESP, Botucatu Sch Med, Dept Vasc Surg, Botucatu, SP, Brazil
dc.description.affiliationSUNY Stony Brook, Med Ctr, Div Vasc Surg, Stony Brook, NY 11794 USA
dc.description.affiliationUNESP, Botucatu Sch Med, Botucatu Clin Hosp, Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista UNESP, Botucatu Sch Med, Dept Vasc Surg, Botucatu, SP, Brazil
dc.description.affiliationUnespUNESP, Botucatu Sch Med, Botucatu Clin Hosp, Botucatu, SP, Brazil
dc.format.extent1751-1760
dc.identifierhttp://dx.doi.org/10.1016/j.avsg.2014.05.013
dc.identifier.citationAnnals Of Vascular Surgery. New York: Elsevier Science Inc, v. 28, n. 7, p. 1751-1760, 2014.
dc.identifier.doi10.1016/j.avsg.2014.05.013
dc.identifier.issn0890-5096
dc.identifier.lattes8240785779318526
dc.identifier.lattes9609324832591382
dc.identifier.urihttp://hdl.handle.net/11449/116442
dc.identifier.wosWOS:000342162000023
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofAnnals Of Vascular Surgery
dc.relation.ispartofjcr1.363
dc.relation.ispartofsjr0,653
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleRecanalization Rates after Acute Deep Vein Thrombosis: A Single-center Experience Using a Newly Proposed Vein Diameter Variation Indexen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
unesp.author.lattes8240785779318526
unesp.author.lattes9609324832591382
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentCirurgia e Ortopedia - FMBpt

Arquivos

Coleções

Botucatu - FMB - Faculdade de Medicina
Artigos - Hospital das Clínicas (HC) - Botucatu