An electrode of the second kind for aspirin determination in tablet formulations

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dc.contributor.authorFerreira, VJF
dc.contributor.authorCavalheiro, ACV
dc.contributor.authorFagnani, E.
dc.contributor.authorde Moraes, M.
dc.contributor.authorPezza, Leonardo [UNESP]
dc.contributor.authorPezza, Helena Redigolo [UNESP]
dc.contributor.authorMelios, C. B.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:25:52Z
dc.date.available2014-05-20T15:25:52Z
dc.date.issued1999-03-01
dc.description.abstractThis paper describes the construction of an electrode of the second kind, Pt\Hg\Hg-2(Salic)(2)\Graphite, sensitive to salicylate. This electrode responds to the salicylate ion with a sensivity of 58.66 mV/decade over the range 6.0x10(-4) - 1.0x10(-1) mol/l at pH 6.0 and an ionic strength of 0.500 - 3.00 mol/l, adjusted with NaClO4. The electrode is easily constructed, shows a fast response time, is low in cost, has excellent response stability, and has a lifetime greater than 18 months, which is much longer than those reported earlier for other systems. The influence of 10 different carboxylate and inorganic anions on the electrode response showed that there was negligible interference by most of these ions. It was used to determine aspirin in tablets (after hydrolysis of acetylsalicylic acid to salicylate) by means of the standard additions method. The results obtained using this electrode for aspirin determination, in three different samples of antithermic drugs, compared favorably with the results given by the British Pharmacopoeia method.en
dc.description.affiliationUNESP, Inst Quim, BR-14801970 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP, Inst Quim, BR-14801970 Araraquara, SP, Brazil
dc.format.extent249-253
dc.identifierhttp://dx.doi.org/10.2116/analsci.15.249
dc.identifier.citationAnalytical Sciences. Tokyo: Japan Soc Analytical Chem, v. 15, n. 3, p. 249-253, 1999.
dc.identifier.doi10.2116/analsci.15.249
dc.identifier.fileWOS000079119200007.pdf
dc.identifier.issn0910-6340
dc.identifier.lattes5978908591853524
dc.identifier.lattes3192125098361121
dc.identifier.orcid0000-0003-0197-7369
dc.identifier.urihttp://hdl.handle.net/11449/36197
dc.identifier.wosWOS:000079119200007
dc.language.isoeng
dc.publisherJapan Soc Analytical Chemistry
dc.relation.ispartofAnalytical Sciences
dc.relation.ispartofjcr1.355
dc.relation.ispartofsjr0,424
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectsalicylate sensitive electrodept
dc.subjectmercury-mercurous salicylatept
dc.subjectpharmaceutical analysispt
dc.subjectsalicylate and acetylsalicylic acid determinationpt
dc.titleAn electrode of the second kind for aspirin determination in tablet formulationsen
dc.typeArtigo
dcterms.licensehttps://www.jstage.jst.go.jp/pub/html/AY04S120_en.html
dcterms.rightsHolderJapan Soc Analytical Chem
unesp.author.lattes5978908591853524
unesp.author.lattes3192125098361121
unesp.author.orcid0000-0003-0197-7369[5]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Química, Araraquarapt

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Artigos - Química Analítica - IQ