Metastatic kidney carcinoma causing paralysis of pelvic limbs in a dog

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dc.contributor.authorCalazans, S. G.
dc.contributor.authorAlves, C. E.F. [UNESP]
dc.contributor.authorZanetti, N. M.
dc.contributor.authorConforti, V. A.
dc.contributor.authorSantilli, J.
dc.contributor.authorAnjos, D. S.
dc.contributor.authorMagalhães, G. M.
dc.contributor.institutionUniversity of Franca-UNIFRAN
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionAdvanced Veterinary Medical Center-CAVET
dc.date.accessioned2018-12-11T16:41:03Z
dc.date.available2018-12-11T16:41:03Z
dc.date.issued2016-01-01
dc.description.abstractA 12-year-old male Maltese dog was presented with a history of shivering episodes. Radiographs revealed a mass in the left kidney that was histopathologically classified as a renal cell carcinoma. After nephrectomy, pelvic limbs became paralyzed. Spinal cord and lung metastases were detected via histopathological examination and confirmed by immunohistochemistry. Both pan-cytoketatin and Ki67 assays tested positive in the kidney, lung, and spinal cord. Interestingly, COX- 2 had mild immunoreactivity in the kidney, but its labeling was intense in the spinal cord and lung. Though seemingly rare, the spinal cord may possibly be a focus point for metastasis of renal cell carcinomas. Because symptoms can easily be misunderstood, late diagnoses would not be uncommon and may hinder clinical management of the disease.en
dc.description.affiliationAnimal Science Graduate Program University of Franca-UNIFRAN, Av. Dr. Armando Salles Oliveira, 201, Parque Univ., Franca
dc.description.affiliationVeterinary Medicine Graduate Program São Paulo State University-UNESP, Av. Prof. Montenegro, s/n
dc.description.affiliationAdvanced Veterinary Medical Center-CAVET, Rua Guimarães Passos, 592
dc.description.affiliationUnespVeterinary Medicine Graduate Program São Paulo State University-UNESP, Av. Prof. Montenegro, s/n
dc.format.extent124-126
dc.identifier.citationPakistan Veterinary Journal, v. 36, n. 1, p. 124-126, 2016.
dc.identifier.issn0253-8318
dc.identifier.scopus2-s2.0-84958175874
dc.identifier.urihttp://hdl.handle.net/11449/168386
dc.language.isoeng
dc.relation.ispartofPakistan Veterinary Journal
dc.relation.ispartofsjr0,365
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectCanine
dc.subjectMetastasis
dc.subjectPan-cytoketatin
dc.subjectRenal neoplasm
dc.subjectSpinal cord
dc.titleMetastatic kidney carcinoma causing paralysis of pelvic limbs in a dogen
dc.typeArtigo

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