Phenylnaphthalic anhydrides from water hyacinth (Pontederia crassipes Mart.)

Costa, Mayra F. [UNESP]; Luiz, Mayara M. [UNESP]; de Souza, Leonardo C. [UNESP]; Tempone, Andre G.; Lago, João Henrique G.; Nascimento, Isabele R. [UNESP]

Phenylnaphthalic anhydrides from water hyacinth (Pontederia crassipes Mart.)

Data

2021-12-01

Autores

Costa, Mayra F.

Luiz, Mayara M.

de Souza, Leonardo C.

Tempone, Andre G.

Lago, João Henrique G.

Nascimento, Isabele R.

Tipo

Artigo

Resumo

Nineteen compounds were isolated from the aerial parts and roots of Pontederia crassipes Mart. [≡ Eichhornia crassipes (Mart.) Solms] (Pontederiaceae), including the new 4-hydroxy-5-phenyl-1,8-naphthalic anhydride (1) and 4-hydroxy-5-(4-hydroxyphenyl)-1,8-naphthalic anhydride (2). In addition, chemically related phenylnaphthalic acid derivatives 1a and 2a were obtained. The structures of the compounds were established by 1D and 2D NMR and ESI-HRMS analysis. 8-Phenylphenalenones 3 and 4 were evaluated for antiprotozoal activity against trypomastigote forms of Trypanosoma cruzi and displayed moderate activity.