Immunomodulatory activities associated with β-glucan derived from Saccharomyces cerevisiae
dc.contributor.author | Pelizon, A. C. [UNESP] | |
dc.contributor.author | Kaneno, Ramon [UNESP] | |
dc.contributor.author | Soares, A. M V C | |
dc.contributor.author | Meira, D. A. | |
dc.contributor.author | Sartori, A. | |
dc.contributor.institution | Universidade de São Paulo (USP) | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2014-05-27T11:21:40Z | |
dc.date.available | 2014-05-27T11:21:40Z | |
dc.date.issued | 2005-11-16 | |
dc.description.abstract | In this study we investigated the effect of β-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 μg of glucan by i.p. route, were assayed. In vivo β-glucan administration primed spleen cells for a higher production of IL-12 and TNF-α when S. aureus was used as a stimulus. In addition, β-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for β-glucan were observed in this work. © 2005 Institute of Physiology, Academy of Sciences of the Czech Republic. | en |
dc.description.affiliation | Department of Microbiology and Immunology Institute de Biosciences State University of Sao Paulo, Sao Paulo | |
dc.description.affiliation | Department of Tropical Diseases and Diagnosis by Image Faculty of Medicine State University of Sao Paulo, Sao Paulo | |
dc.description.affiliation | Department of Microbiology and Immunology Instituto de Biociências Universidade Estadual Paulista (UNESP) | |
dc.description.affiliationUnesp | Department of Microbiology and Immunology Instituto de Biociências Universidade Estadual Paulista (UNESP) | |
dc.format.extent | 557-564 | |
dc.identifier | http://www.biomed.cas.cz/physiolres/2005/issue5/pelizon.htm | |
dc.identifier.citation | Physiological Research, v. 54, n. 5, p. 557-564, 2005. | |
dc.identifier.file | 2-s2.0-27644525584.pdf | |
dc.identifier.issn | 0862-8408 | |
dc.identifier.lattes | 8845835550637809 | |
dc.identifier.lattes | 4977572416129527 | |
dc.identifier.orcid | 0000-0002-4292-3298 | |
dc.identifier.scopus | 2-s2.0-27644525584 | |
dc.identifier.uri | http://hdl.handle.net/11449/68495 | |
dc.language.iso | eng | |
dc.relation.ispartof | Physiological Research | |
dc.relation.ispartofjcr | 1.324 | |
dc.relation.ispartofsjr | 0,568 | |
dc.rights.accessRights | Acesso aberto | |
dc.source | Scopus | |
dc.subject | β-glucan | |
dc.subject | Fungicidal activity | |
dc.subject | IL-12 | |
dc.subject | NK activity | |
dc.subject | TNF-α | |
dc.subject | beta glucan | |
dc.subject | interleukin 12 | |
dc.subject | tumor necrosis factor alpha | |
dc.subject | animal cell | |
dc.subject | animal experiment | |
dc.subject | cell activity | |
dc.subject | controlled study | |
dc.subject | cytokine production | |
dc.subject | drug effect | |
dc.subject | female | |
dc.subject | fungicidal activity | |
dc.subject | immunomodulation | |
dc.subject | mouse | |
dc.subject | natural killer cell | |
dc.subject | nonhuman | |
dc.subject | peritoneum cell | |
dc.subject | Saccharomyces cerevisiae | |
dc.subject | spleen cell | |
dc.subject | target cell | |
dc.subject | Animals | |
dc.subject | Antifungal Agents | |
dc.subject | beta-Glucans | |
dc.subject | Cytokines | |
dc.subject | Dose-Response Relationship, Drug | |
dc.subject | Female | |
dc.subject | Immunologic Factors | |
dc.subject | Killer Cells, Natural | |
dc.subject | Mice | |
dc.subject | Mice, Inbred C57BL | |
dc.subject | Paracoccidioides | |
dc.title | Immunomodulatory activities associated with β-glucan derived from Saccharomyces cerevisiae | en |
dc.type | Artigo | |
unesp.author.lattes | 4977572416129527[5] | |
unesp.author.lattes | 8845835550637809[2] | |
unesp.author.orcid | 0000-0003-4557-3331[5] | |
unesp.author.orcid | 0000-0002-4292-3298[2] | |
unesp.campus | Universidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatu | pt |
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