Crystallization and preliminary X-ray diffraction analysis of a Lys49-PLA 2 homologue from Cerrophidion Godmani venom
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1998-12-01
Autores
De Azevedo, W. F. [UNESP]
Ward, R. J. [UNESP]
Gutiérrez, J. M.
Diaz-Oreiro, C. [UNESP]
Arni, R. K. [UNESP]
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Lys49-Phospholipase A 2 (Lys49-PLA 2) homologues damage membranes by a Ca 2+-independent mechanism which does not involve catalytic activity. The myotoxic Lys-49 phospholipase myotoxin II from Cerrophidion (Bothrops) godmani has been crystallized, and X-ray diffraction data were collected to 2.8 Å resolution. Preliminary analysis reveals the presence of one molecule in the asymmetric unit.
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Protein and Peptide Letters, v. 5, n. 2, p. 121-126, 1998.