Evaluation of clinical, ultrasonographic and hysteroscopic parameters in the differentiation of endometrial polyps and cancer of endometrium

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dc.contributor.authorDias, Rogerio [UNESP]
dc.contributor.authorDias, Daniel Spadoto [UNESP]
dc.contributor.authorDias, Flávia Neves Bueloni [UNESP]
dc.contributor.authorModotti, Waldir Pereira [UNESP]
dc.contributor.authorLasmar, Ricardo Bassil [UNESP]
dc.contributor.authorLeite, Nilton José [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2016-04-01T18:43:22Z
dc.date.available2016-04-01T18:43:22Z
dc.date.issued2012
dc.description.abstractStudy Objective: To evaluate the diagnostic accuracy of transvaginal ultrasound and office hysteroscopy in the differentiation between endometrial polyps and endometrial adenocarcinoma. Design: This is a prospective 100 women longitudinal study, 24 to 80 years, submitted to hysteroscopic polypectomy (n = 80) or surgery due to endometrial adenocarcinoma (n = 20), from january 2010 to December 2011. Clinical, ultrasonographic and hysteroscopic parameters were analyzed and compared with histopathologic find. Statistical analysis were performed utilizing the Tukey, Kruskal-Wallis, Dunn and Mann-Whitney test, with a confidence interval of 95% and p\0, 05 statiscally significant. Setting: Botucatu Medical School. Intervention: Prospective analysis of clinical, ultrasonographic and hysteroscopic parameters in patients with diagnosis suspected of endometrial polyps and adenocarcinoma of endometrium were performed. According to the diagnosis, hysteroscopic polypectomy or pan hysterectomy with lymph node sampling was realized. After the surgery and histopathological study, statistical analysis of parameters was performed and the results were compared between groups. It was Research Ethics Committee approved. Measurements and Main Results: There were no differences between age, BMI, menopause, TH use and associated diseases among groups. The main symptom of endometrial cancer was the postmenopausal bleeding, affecting 84,2% of women against 34,8% of polypectomy group. The majority of women with endometrial polyps were asymptomatic. Transvaginal ultrasonography showed no ability to differentiate cases of endometrial cancer compared with the cases of endometrial polyps, considering the presence of endometrial thickness and blood flow on color Doppler. Office hysteroscopy showed significant changes in 75% of the adenocarcinoma cases, especially the presence of diffuse hypervascularity with atypical vessels. Conclusion: Still remains an inability to establish clinical parameters and reliable ultrasound imaging to differentiate endometrial polyps and cancer of endometrium. Attention should be given to hysteroscopic exams presenting diffuse endometrial hypervascularization with architectural distortion of the vessels. The recommendation of our service remains the systematic removal of all endometrial polyps.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Ginecologia e Obstetrícia, Botucatu, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Ginecologia e Obstetrícia, Botucatu, SP, Brasil
dc.format.extentS109-S109
dc.identifierhttp://dx.doi.org/10.1016/j.jmig.2012.08.710
dc.identifier.citationJournal of Minimally Invasive Gynecology, v. 19, n. 6, p. S109-S109, 2012.
dc.identifier.doi10.1016/j.jmig.2012.08.710
dc.identifier.fileISSN1553-4650-2012-19-06-S109-S109.pdf
dc.identifier.issn1553-4650
dc.identifier.lattes9476843874583499
dc.identifier.lattes9476843874583499
dc.identifier.lattes9476843874583499
dc.identifier.urihttp://hdl.handle.net/11449/136935
dc.language.isoeng
dc.relation.ispartofJournal of Minimally Invasive Gynecology
dc.relation.ispartofjcr3.061
dc.relation.ispartofsjr1,105
dc.rights.accessRightsAcesso aberto
dc.sourceCurrículo Lattes
dc.titleEvaluation of clinical, ultrasonographic and hysteroscopic parameters in the differentiation of endometrial polyps and cancer of endometriumen
dc.typeArtigo
unesp.author.lattes9476843874583499
unesp.author.lattes9476843874583499
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentGinecologia e Obstetrícia - FMBpt

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