Comparison of hydrophilic and hydrophobic nano topographic surfaces of titanium alloys on pre-osteoblastic cell interaction

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dc.contributor.authorde Oliveira, Diego Pedreira
dc.contributor.authorMicocci, Kelli Cristina [UNESP]
dc.contributor.authorde Almeida, Gustavo Foresto Brito
dc.contributor.authorOtuka, Adriano José Galvani [UNESP]
dc.contributor.authorMendonça, Cléber Renato
dc.contributor.authorSelistre-De-Araujo, Heloisa Sobreiro
dc.contributor.authorBolfarini, Claudemiro
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade Federal de Uberlândia (UFU)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2023-07-29T13:58:33Z
dc.date.available2023-07-29T13:58:33Z
dc.date.issued2023-07-01
dc.description.abstractThis work aimed to assess the influence of different structured substrates with hydrophilic and hydrophobic properties on micro and nano topographies developed on titanium alloys over pre-osteoblastic cell behavior. Nano topography influences small dimension levels of cell morphology by inducing filopodia formation in cell membranes, irrespectively to the wettability behavior of the surface. Therefore, micro and nanostructured surfaces of titanium-based samples using different techniques of surface modification processing, such as chemical treatments, micro-arc anodic oxidation (MAO), and MAO combined to laser irradiation were developed. Isotropic and anisotropic texture morphologies, wettability, topological parameters and compositional alterations were measured after the surface treatments. Finally, cell viability, adhesion and morphological responses were assessed to investigate the influence of distinct topologies on osteoblastic cells aiming to encounter the conditions to better promote mineralization events. Our study demonstrated that the hydrophilic behavior improves cell adhesion, amplified when effective surface area increases. Surfaces presenting nano topography have a direct influence on cell morphology and play a key role for filopodia formation.en
dc.description.affiliationDepartment of Materials Engineering Federal University of São Carlos, São Carlos
dc.description.affiliationDepartment of Physiological Sciences Federal University of São Carlos
dc.description.affiliationCenter for the Study of Social Insects São Paulo State University, SP
dc.description.affiliationInstituto de Física Universidade Federal de Uberlândia, MG
dc.description.affiliationDepartamento de Física UNESP, SP
dc.description.affiliationSão Carlos Institute of Physics University of São Paulo, SP
dc.description.affiliationUnespCenter for the Study of Social Insects São Paulo State University, SP
dc.description.affiliationUnespDepartamento de Física UNESP, SP
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.identifierhttp://dx.doi.org/10.1088/2057-1976/acd786
dc.identifier.citationBiomedical Physics and Engineering Express, v. 9, n. 4, 2023.
dc.identifier.doi10.1088/2057-1976/acd786
dc.identifier.issn2057-1976
dc.identifier.scopus2-s2.0-85161527344
dc.identifier.urihttp://hdl.handle.net/11449/248962
dc.language.isoeng
dc.relation.ispartofBiomedical Physics and Engineering Express
dc.sourceScopus
dc.subjectcell behavior
dc.subjectmicro topography
dc.subjectnano topography
dc.subjectsurface treatment
dc.subjecttitanium alloys
dc.titleComparison of hydrophilic and hydrophobic nano topographic surfaces of titanium alloys on pre-osteoblastic cell interactionen
dc.typeArtigo
unesp.author.orcid0000-0002-2372-7814[6]

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Rio Claro - CEIS - Centro de Estudos de Insetos Sociais