Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial

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dc.contributor.authorBonardi, João Paulo [UNESP]
dc.contributor.authorPereira, Rodrigo dos Santos
dc.contributor.authorMourão, Carlos F.
dc.contributor.authorCoelho Mendes, Bruno [UNESP]
dc.contributor.authorLowenstein, Adam
dc.contributor.authorMontemezzi, Pietro
dc.contributor.authorGiubilato, Flavio [UNESP]
dc.contributor.authorOkamoto, Roberta [UNESP]
dc.contributor.authorHochuli-Vieira, Eduardo [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversity of Grande Rio-UNIGRANRIO
dc.contributor.institutionTufts University School of Dental Medicine
dc.contributor.institutionSan Raffaele Hospital
dc.date.accessioned2023-07-29T13:41:44Z
dc.date.available2023-07-29T13:41:44Z
dc.date.issued2023-02-01
dc.description.abstractThe aim of the present study is to compare the biphasic calcium phosphate (BCP) using two different forms—(1) granules and (2) paste—in human maxillary sinus bone reconstruction as a split-mouth study using histomorphometric and immunolabeling for osteocalcin. Ten patients with bilateral maxillary posterior partial edentulism were selected in order to reconstruct bone height. They were divided into two groups: BCPG and BCP-P. After six months of bone healing, biopsies were harvested to assess the new bone formation and immunostaining for osteocalcin. The BCP g group had the following results: mean of bone formation in pristine bone 49.4 ± 21.6%, intermediate 49.4 ± 16.2%, and apical 55.3 ± 21.4%. The group BCP-P had a mean of 41.9 ± 17.3% in the pristine bone region, 37.5 ± 7.8% for intermediate, and 39.0 ± 13.5% for apical. The osteocalcin immunolabeling was high for both groups, demonstrating bone calcification. Thus, the two biomaterials present suitable results for the placement of dental implants.en
dc.description.affiliationDepartment of Oral & Maxillofacial Surgery Aracatuba School of Dentistry Sao Paulo State University
dc.description.affiliationDepartment of Oral & Maxillofacial Surgery University of Grande Rio-UNIGRANRIO
dc.description.affiliationDepartment of Periodontology Division of Dental Research Administration Tufts University School of Dental Medicine
dc.description.affiliationDepartment of Dentistry San Raffaele Hospital
dc.description.affiliationDepartment of Human Anatomy Aracatuba School of Dentistry Sao Paulo State University
dc.description.affiliationDepartment of Diagnostic and Surgery Araraquara School of Dentistry Sao Paulo State University
dc.description.affiliationUnespDepartment of Oral & Maxillofacial Surgery Aracatuba School of Dentistry Sao Paulo State University
dc.description.affiliationUnespDepartment of Human Anatomy Aracatuba School of Dentistry Sao Paulo State University
dc.description.affiliationUnespDepartment of Diagnostic and Surgery Araraquara School of Dentistry Sao Paulo State University
dc.identifierhttp://dx.doi.org/10.3390/ma16031059
dc.identifier.citationMaterials, v. 16, n. 3, 2023.
dc.identifier.doi10.3390/ma16031059
dc.identifier.issn1996-1944
dc.identifier.scopus2-s2.0-85148046032
dc.identifier.urihttp://hdl.handle.net/11449/248357
dc.language.isoeng
dc.relation.ispartofMaterials
dc.sourceScopus
dc.subjectbiomaterials
dc.subjectbone substitutes
dc.subjectsinus floor augmentation
dc.titleClinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trialen
dc.typeArtigo
unesp.author.orcid0000-0003-2509-8633[2]
unesp.author.orcid0000-0001-5775-0222[3]
unesp.author.orcid0000-0002-0751-4894[5]

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Artigos - Cirurgia e Clínica Integrada - FOA
Artigos - Diagnóstico e Cirurgia - FOAR