Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface
Carregando...
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Tipo
Artigo
Direito de acesso
Resumo
Miranda and Bueno recently demonstrated that chemical hardness could be experimentally measured and used as a chemical reactivity index of electrochemical interfaces. Herein, we applied this reactivity index concept to sense biological targets of medical interest, demonstrating the advantages of using this concept in improving the reproducibility of signal analysis during the construction of analytical curves. An analytical signal was obtained for sensing based on the effective chemical hardness of the quantum capacitive electroactive moieties of the interface, demonstrating advantages for calibration compared with methods based solely on the inverse of capacitance. The clinical value of this concept was demonstrated by studying the biological interaction of paclitaxel withβ -tubulin.
Descrição
Palavras-chave
Analytical curve, Calibration procedure, Conceptual density functional theory, Electrochemical sensor, Quality control and reproducibility, Quantum capacitance
Idioma
Inglês
Citação
IEEE Access, v. 9, p. 166446-166454.
