Fruit of the jambolan tree (Eugenia jambolana Lam.) and experimental diabetes

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dc.contributor.authorPepato, Maria Teresa [UNESP]
dc.contributor.authorMori, D. M.
dc.contributor.authorBaviera, Amanda Martins [UNESP]
dc.contributor.authorHarami, J. B.
dc.contributor.authorVendramini, Regina Célia [UNESP]
dc.contributor.authorBrunetti, Iguatemy Lourenço [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:24:40Z
dc.date.available2014-05-20T13:24:40Z
dc.date.issued2005-01-01
dc.description.abstractThe fruit of Indian Eugenia jambolana have been shown to have therapeutic properties, but because the therapeutic potential of a plant is related to the geographic region in which the plant was grown and to the part of the plant used, we investigated Brazilian Eugenia jambolana fruit using the same preparation and experimental methods as have been used in India. The well-established metabolic cage model was used to evaluate the physiological and metabolic parameters associated with streptozotocin-induced diabetes in rats (n = 10) which had been administered, by gavage, 50 mg per day of lyophilised Eugenia jambolana fruit-pulp extract for 41 days. We found that, compared to untreated controls, rats treated with the lyophilised fruit-pulp showed no observable difference in body weight, food or water intake, urine volume, glycaemia, urinary urea and glucose, hepatic glycogen, or on serum levels of total cholesterol, HDL cholesterol or triglycerides. No change was observed in the masses of epididymal or retroperitoneal adipose tissue or of soleus or extensor digitorum longus muscles. This lack of any apparent effect on the diabetes may be attributable to the regional ecosystem where the fruit was collected and/or to the severity of the induced diabetes. (C) 2004 Elsevier B.V.. All rights reserved.en
dc.description.affiliationUNESP, Fac Ciências Farmaceut, Dept Anal Clin, BR-14801902 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP, Fac Ciências Farmaceut, Dept Anal Clin, BR-14801902 Araraquara, SP, Brazil
dc.format.extent43-48
dc.identifierhttp://dx.doi.org/10.1016/j.jep.2004.07.029
dc.identifier.citationJournal of Ethnopharmacology. Clare: Elsevier Sci Ireland Ltd, v. 96, n. 1-2, p. 43-48, 2005.
dc.identifier.doi10.1016/j.jep.2004.07.029
dc.identifier.issn0378-8741
dc.identifier.lattes3736475025187750
dc.identifier.lattes7641979287850489
dc.identifier.urihttp://hdl.handle.net/11449/7730
dc.identifier.wosWOS:000225869600005
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofJournal of Ethnopharmacology
dc.relation.ispartofjcr3.115
dc.relation.ispartofsjr1,150
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectEugenia jambolanapt
dc.subjectfruitpt
dc.subjectstreptozotocin-diabetic ratspt
dc.subjectanti-diabetic activitypt
dc.subjectanti-hyperglycaemic effectpt
dc.titleFruit of the jambolan tree (Eugenia jambolana Lam.) and experimental diabetesen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
unesp.author.lattes3736475025187750[3]
unesp.author.lattes7641979287850489
unesp.author.orcid0000-0003-0987-5295[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentAnálises Clínicas - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas