Comparative analysis of two different models of swimming applied to pregnant rats born small for pregnant age

dc.contributor.authorCorvino, Silvana B. [UNESP]
dc.contributor.authorDamasceno, Débora C. [UNESP]
dc.contributor.authorSinzato, Yuri K. [UNESP]
dc.contributor.authorNetto, Aline O. [UNESP]
dc.contributor.authorMacedo, Nathália C. D. [UNESP]
dc.contributor.authorZambrano, Elena
dc.contributor.authorVolpato, Gustavo T. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionCidade do México
dc.contributor.institutionUniversidade Federal de Mato Grosso/UFMT
dc.date.accessioned2018-12-11T17:11:19Z
dc.date.available2018-12-11T17:11:19Z
dc.date.issued2017-01-01
dc.description.abstractThe aim of this study was to compare two models of swimming applied to pregnant rats born small for pregnancy age (SPA). Diabetes was chemically induced in adult female rats to develop an inadequate intrauterine environment, leading to birth of a SPA offspring. In adulthood, the female SPA rats were mated and submitted to different swimming programs. The exercise program 1 (Ex1) consisted of swimming for 15 minutes, followed by 15 minutes of rest and another 15 minutes of swimming, 3 days a week before and during pregnancy. Another program (Ex2) was applied during 60 minutes uninterrupted a day, 6 days/ week during pregnancy. The pregnant rats presented no interference on body weight and glycemia. The rats submitted to Ex2 model showed decreased insulin and blood glucose levels by oral glucose tolerance test, and reduction in area under curve values. The offspring from dams submitted to both exercise protocols presented an increased rate of newborns SPA. However, the offspring from Ex2 dams showed percentage twice higher of newborns SPA than Ex1 offspring. Our data suggests that continuous exercise of 60 min/ day ameliorated the enhanced peripheral insulin sensitivity in growth-restricted females. However, this protocol employed at pregnancy leads to intrauterine growth restriction.en
dc.description.affiliationLaboratório de Pesquisa Experimental de Ginecologia e Obstetrícia Faculdade de Medicina de Botucatu Universidade Estadual Paulista/UNESP Distrito de Rubião Jr s/n
dc.description.affiliationDepartment of Reproductive Biology Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Cidade do México
dc.description.affiliationLaboratório de Fisiologia de Sistemas e Toxicologia Reprodutiva Instituto de Ciências Biológicas e da Saúde Universidade Federal de Mato Grosso/UFMT, Av. Valdon Varjão, 6390
dc.description.affiliationUnespLaboratório de Pesquisa Experimental de Ginecologia e Obstetrícia Faculdade de Medicina de Botucatu Universidade Estadual Paulista/UNESP Distrito de Rubião Jr s/n
dc.format.extent223-230
dc.identifierhttp://dx.doi.org/10.1590/0001-3765201720160285
dc.identifier.citationAnais da Academia Brasileira de Ciencias, v. 89, n. 1, p. 223-230, 2017.
dc.identifier.doi10.1590/0001-3765201720160285
dc.identifier.fileS0001-37652017000100223.pdf
dc.identifier.issn1678-2690
dc.identifier.issn0001-3765
dc.identifier.scieloS0001-37652017000100223
dc.identifier.scopus2-s2.0-85017627827
dc.identifier.urihttp://hdl.handle.net/11449/174480
dc.language.isoeng
dc.relation.ispartofAnais da Academia Brasileira de Ciencias
dc.relation.ispartofsjr0,418
dc.relation.ispartofsjr0,418
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectDiabetes
dc.subjectExercise
dc.subjectOffspring
dc.subjectPregnancy
dc.subjectRats
dc.titleComparative analysis of two different models of swimming applied to pregnant rats born small for pregnant ageen
dc.typeArtigo

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