Analog modeling of human cognitive functions with tripartite synapses
| dc.contributor.author | Pereira Jr., Alfredo | |
| dc.contributor.author | Furlan, Fábio Augusto | |
| dc.contributor.institution | Universidade de São Paulo (USP) | |
| dc.contributor.institution | University of Marília | |
| dc.date.accessioned | 2022-04-28T18:56:22Z | |
| dc.date.available | 2022-04-28T18:56:22Z | |
| dc.date.issued | 2010-10-14 | |
| dc.description.abstract | Searching for an understanding of how the brain supports conscious processes, cognitive scientists have proposed two main classes of theory: Global Workspace and Information Integration theories. These theories seem to be complementary, but both still lack grounding in terms of brain mechanisms responsible for the production of coherent and unitary conscious states. Here we propose - following James Robertson's Astrocentric Hypothesis - that conscious processing is based on analog computing in astrocytes. The hardware for these computations is calcium waves mediated by adenosine triphosphate signaling. Besides presenting our version of this hypothesis, we also review recent findings on astrocyte morphology that lend support to their functioning as Local Hubs (composed of protoplasmic astrocytes) that integrate synaptic activity, and as a Master Hub (composed, in the human brain, by a combination of interlaminar, fibrous, polarized and varicose projection astrocytes) that integrates whole-brain activity. © 2010 Springer-Verlag Berlin Heidelberg. | en |
| dc.description.affiliation | Institute of Biosciences State University of São Paulo, Botucatu | |
| dc.description.affiliation | School of Medicine University of Marília, Marília | |
| dc.format.extent | 623-635 | |
| dc.identifier | http://dx.doi.org/10.1007/978-3-642-15223-8_35 | |
| dc.identifier.citation | Studies in Computational Intelligence, v. 314, p. 623-635. | |
| dc.identifier.doi | 10.1007/978-3-642-15223-8_35 | |
| dc.identifier.issn | 1860-949X | |
| dc.identifier.scopus | 2-s2.0-77957732170 | |
| dc.identifier.uri | http://hdl.handle.net/11449/219598 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Studies in Computational Intelligence | |
| dc.source | Scopus | |
| dc.title | Analog modeling of human cognitive functions with tripartite synapses | en |
| dc.type | Trabalho apresentado em evento |