Anti-Erosive Effect of Solutions Containing Sodium Fluoride, Stannous Chloride, and Selected Film-Forming Polymers

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dc.contributor.authorBezerra, Sávio J.C.
dc.contributor.authorJoão-Souza, Samira H.
dc.contributor.authorAoki, Idalina V.
dc.contributor.authorBorges, Alessandra B. [UNESP]
dc.contributor.authorHara, Anderson T.
dc.contributor.authorScaramucci, Taís
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversity of Bern
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionIndiana University School of Dentistry
dc.date.accessioned2019-10-06T15:22:38Z
dc.date.available2019-10-06T15:22:38Z
dc.date.issued2019-04-01
dc.description.abstractThe aim of this study was to evaluate the anti-erosive effect of solutions containing sodium fluoride (F: 225 ppm F), stannous chloride (Sn: 800 ppm Sn2+), and some film-forming polymers (Gantrez: Poly [methylvinylether-alt-maleic anhydride]; PGA: propylene glycol alginate; Plasdone: poly[vinylpyrrolidone]; and CMC: carboxymethylcellulose). Solutions were tested in an erosion-remineralization cycling model, using enamel and dentin specimens (<italic>n</italic> = 10, for each substrate). Distilled water was the negative control. Cycling consisted of 120 min immersion in human saliva, 5 min in 0.3% citric acid solution, and 120 min of exposure to human saliva, 4×/day, for 5 days. Treatment with solutions (pH = 4.5) was carried out 2×/day, for 2 min. Surface loss (SL) was evaluated with optical profilometry. Zeta potential of hydroxyapatite crystals was determined after treatment with the solutions. Data were statistically analyzed (α = 0.05). For enamel, all polymers showed significantly lower SL (in μm) than the control (11.09 ± 0.94), except PGA (10.15 ± 1.25). PGA significantly improved the protective effect of F (4.24 ± 0.97 vs. 5.64 ± 1.60, respectively). None of the polymers increased the protection of F+Sn (5.13 ± 0.78). For dentin, only Gantrez (11.40 ± 0.97) significantly reduced SL when compared with the negative control (12.76 ± 0.75). No polymer was able to enhance the effect of F (6.28 ± 1.90) or F+Sn (7.21 ± 1.13). All fluoridated solutions demonstrated significantly lower SL values than the control for both substrates. Treatment of hydroxyapatite nanoparticles with all solutions resulted in more negative zeta potentials than those of the control, except Plasdone, PGA, and F+Sn+PGA, the latter two presenting the opposite effect. In conclusion, Gantrez, Plasdone, and CMC exhibited an anti-erosive effect on enamel. PGA increased the protection of F. For dentin, only Gantrez reduced erosion.en
dc.description.affiliationDepartment of Restorative Dentistry School of Dentistry University of São Paulo
dc.description.affiliationDepartment of Restorative Preventive and Pediatric Dentistry School of Dental Medicine University of Bern
dc.description.affiliationDepartment of Chemical Engineering Polytechnic School São Paulo University - USP
dc.description.affiliationDepartment of Restorative Dentistry Institute of Science and Technology São Paulo State University - UNESP
dc.description.affiliationDepartment of Cariology Operative Dentistry and Dental Public Health Indiana University School of Dentistry
dc.description.affiliationUnespDepartment of Restorative Dentistry Institute of Science and Technology São Paulo State University - UNESP
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: #2015/11402-8
dc.format.extent305-313
dc.identifierhttp://dx.doi.org/10.1159/000493388
dc.identifier.citationCaries Research, v. 53, n. 3, p. 305-313, 2019.
dc.identifier.doi10.1159/000493388
dc.identifier.issn1421-976X
dc.identifier.issn0008-6568
dc.identifier.scopus2-s2.0-85055659385
dc.identifier.urihttp://hdl.handle.net/11449/187008
dc.language.isoeng
dc.relation.ispartofCaries Research
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectDental erosion
dc.subjectFluoride
dc.subjectPolymers
dc.subjectStannous chloride
dc.titleAnti-Erosive Effect of Solutions Containing Sodium Fluoride, Stannous Chloride, and Selected Film-Forming Polymersen
dc.typeArtigo

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