Efeitos hipotensivo e diurético dos extratos aquosos de pitanga (Eugenia uniflora L.) e jambolão (Eugenia jambolana Lam.) em ratos normotensos anestesiados

dc.contributor.authorCirqueira, R. T.
dc.contributor.authorAlves, M. J Q F [UNESP]
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:21:16Z
dc.date.available2014-05-27T11:21:16Z
dc.date.issued2005-02-01
dc.description.abstractPlants that possess a diuretic effect are widely used by people in the treatment of some important diseases as edema and hypertension. The objective of this work was to study the effects of pitanga and jambos aqueous extracts (AE) about the arterial pressure (AP) and urinary flow (V) in normotensive and anesthetized rats. The AE were prepared for the decoction method and administrated for intragastric way in different concentrations: 10%, 15%, 20% and 25%. These concentrations corresponded respectively at doses of 56, 94, 145, 172 mg of pitanga dried extract /Kg and 44, 73, 83, 95 mg of jambos dried extract/Kg. The animals were divided in nine groups with seven individuals (n=7): control (C), P-10%, P-15%, P-20%, P-25%, J-10%, J-15%, J-20% and J-25%. The rats were anesthetized (hypnol 3%) and submitted to tracheotomy. The left carotide artery was catheterized to measure the AP through a mercury manometer, in periods of 15 minutes. The bladder was catheterized for urine collection and to measure the V, in periods of 30 minutes. The experimental protocol was divided in four periods of 30 minutes each: basal (to evaluate of the basal parameters) and experimental (Exp) 1, 2 and 3 (after the administration of the AE). The results were analyzed for ANOVA and Tukey (X±SD, p<0.05). In the C group did have not alteration of the AP basal but the V basal increased. In the experimental groups (AE of P and J) had significative decline in the AP basal: 34% (P-10%), 20% (P-15%), 21% (P-20%), 31% (P-25%), 24% (J-10%), 20% (J-15%) 16% (J-20%) and 29% (J-25%). Moreover, the administration of AE increased the V basal in: 280% (P-15%) and 192% (J-20%). The results showed that the plants evaluated are hypotensive and diuretic.en
dc.description.affiliationDepartamento de Biologia Faculdade de Filosofia, Ciências e Letras USP, Avenida Bandeirantes, 3900, CEP14040-901, Ribeirao Preto, SP
dc.description.affiliationDepartamento de Fisiologia Instituto de Biociências UNESP, Rubião Júnior s/n
dc.description.affiliationUnespDepartamento de Fisiologia Instituto de Biociências UNESP, Rubião Júnior s/n
dc.format.extent86-91
dc.identifierhttp://www.ibb.unesp.br/Home/Departamentos/Botanica/RBPM-RevistaBrasileiradePlantasMedicinais/artigo_12_v7_n2.pdf
dc.identifier.citationRevista Brasileira de Plantas Medicinais, v. 7, n. 2, p. 86-91, 2005.
dc.identifier.file2-s2.0-21344445969.pdf
dc.identifier.issn1516-0572
dc.identifier.scopus2-s2.0-21344445969
dc.identifier.urihttp://hdl.handle.net/11449/68131
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Plantas Medicinais
dc.relation.ispartofsjr0,199
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectDiuretic
dc.subjectHypotensive
dc.subjectJambos
dc.subjectMedicinal plants
dc.subjectPitanga
dc.subjectEugenia uniflora extract
dc.subjectplant extract
dc.subjectSyzygium cumini extract
dc.subjectunclassified drug
dc.subjectanimal experiment
dc.subjectantihypertensive activity
dc.subjectarterial pressure
dc.subjectcontrolled study
dc.subjectdiuresis
dc.subjectdiuretic activity
dc.subjectEugenia
dc.subjecteugenia jambolana
dc.subjecteugenia uniflora
dc.subjectmedicinal plant
dc.subjectmicturition
dc.subjectnonhuman
dc.subjectrat
dc.subjectAnimalia
dc.subjectEugenia uniflora
dc.subjectSyzygium cumini
dc.titleEfeitos hipotensivo e diurético dos extratos aquosos de pitanga (Eugenia uniflora L.) e jambolão (Eugenia jambolana Lam.) em ratos normotensos anestesiadospt
dc.title.alternativeHypotensive and diuretic effects of pitanga (Eugenia uniflora L.) and jambos (Eugenia jambolana Lam.) aqueous extracts in normotensive anesthetized ratsen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rbpm/paboutj.htm#03
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

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