Prospective study for the development of emulsion systems containing natural oil products

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dc.contributor.authorXavier, F. H.
dc.contributor.authorSilva, K. G.H.
dc.contributor.authorFarias, I. E.G.
dc.contributor.authorMorais, A. R.V.
dc.contributor.authorAlencar, E. N.
dc.contributor.authorAraújo, I. B.
dc.contributor.authorOliveira, A. G. [UNESP]
dc.contributor.authorEgito, E. S.T.
dc.contributor.institutionPrograma de Pós-Graduação em Ciências da Saúde (PPGCSa)
dc.contributor.institutionLaSiD
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T18:58:01Z
dc.date.available2022-04-28T18:58:01Z
dc.date.issued2012-01-01
dc.description.abstractCopaiba oil, when used as anti-inflammatory and anti-infective agent, presents two major problems: i) low absorption and bioavailability and ii) an unpleasant taste. Once an appropriate emulsion was achieved, the samples were prepared using different surfactant binary mixtures to obtain a range of HLB values between 45 and 16.5. The HLB value of copaiba oil was 14.8; this system has been stable for more than one year, and the pseudo-ternary diagrams were useful to describe the component proportions. These results indicated that the copaiba oil emulsion might be a promising vehicle for topical delivery of drugs and active cosmetic ingredients.en
dc.description.affiliationUniversidade Federal do Rio Grande do Norte (UFRN) Centro de Ciências da Saúde (CCS) Programa de Pós-Graduação em Ciências da Saúde (PPGCSa), Av. Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, 59010-180, Natal-RN
dc.description.affiliationUFRN Departamento de Farmácia LaSiD, Av. Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, 59010-180, Natal-RN
dc.description.affiliationUNESP Faculdade de Ciências Farmacêuticas Grupo de Sistemas Biomiméticos, Rodovia Araraquara-Jau, km 01, 14801-902, Araraquara-SP
dc.description.affiliationUnespUNESP Faculdade de Ciências Farmacêuticas Grupo de Sistemas Biomiméticos, Rodovia Araraquara-Jau, km 01, 14801-902, Araraquara-SP
dc.format.extent367-372
dc.identifierhttp://dx.doi.org/10.1016/s1773-2247(12)50061-4
dc.identifier.citationJournal of Drug Delivery Science and Technology, v. 22, n. 4, p. 367-372, 2012.
dc.identifier.doi10.1016/s1773-2247(12)50061-4
dc.identifier.issn1773-2247
dc.identifier.scopus2-s2.0-84865835486
dc.identifier.urihttp://hdl.handle.net/11449/219833
dc.language.isoeng
dc.relation.ispartofJournal of Drug Delivery Science and Technology
dc.sourceScopus
dc.subjectCopaiba oil
dc.subjectEmulsion
dc.subjectHydrophilic-lipophilic balance
dc.subjectPseudo-ternary phase diagram
dc.subjectStability analysis
dc.titleProspective study for the development of emulsion systems containing natural oil productsen
dc.typeArtigo

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