Fluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharides

dc.contributor.authorPagotto, Leonardo Libardi
dc.contributor.authorSpinola, Manuela Da Silva [UNESP]
dc.contributor.authorNóbrega, Diego Figueiredo
dc.contributor.authorCury, Jaime Aparecido
dc.contributor.authorTenuta, Livia Maria Andaló
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionCesmac University Center
dc.contributor.institutionUniversity of Michigan
dc.date.accessioned2021-06-25T10:27:05Z
dc.date.available2021-06-25T10:27:05Z
dc.date.issued2021-01-01
dc.description.abstractExtracellular polysaccharides (EPS), mainly the insoluble ones, increase the cariogenicity of dental biofilm, but whether they interfere with the binding and retention of fluoride is unknown. EPS-rich (EPS+) and EPS-poor (EPS-) pellets of Streptococcus mutans were formed and treated with increasing fluoride concentrations (0, 0.1, 1, or 10 mM). A concentration-dependent fluoride binding was observed in both EPS-and EPS+ pellets, but the presence of EPS did not affect the retention of fluoride in the pellets. In conclusion, the data suggest that a matrix of dental biofilm rich in EPS does not affect fluoride retention in the biofilm.en
dc.description.affiliationDepartment of Biosciences Piracicaba Dental School University of Campinas
dc.description.affiliationDepartment of Restorative Dentistry Institute of Science and Technology Unesp
dc.description.affiliationProfessional Masters Research in Health Cesmac University Center
dc.description.affiliationDepartment of Cariology Restorative Sciences and Endodontics University of Michigan
dc.description.affiliationUnespDepartment of Restorative Dentistry Institute of Science and Technology Unesp
dc.identifierhttp://dx.doi.org/10.1159/000515115
dc.identifier.citationCaries Research.
dc.identifier.doi10.1159/000515115
dc.identifier.issn1421-976X
dc.identifier.issn0008-6568
dc.identifier.scopus2-s2.0-85103569522
dc.identifier.urihttp://hdl.handle.net/11449/206135
dc.language.isoeng
dc.relation.ispartofCaries Research
dc.sourceScopus
dc.titleFluoride Binding to Streptococcus mutans Pellets Rich in Extracellular Polysaccharidesen
dc.typeArtigo

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