Animal modeling in bone research-Should we follow the White Rabbit?

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dc.contributor.authorMacedo, Aline Schafrum
dc.contributor.authorFeitosa, Caroline Cezaretti
dc.contributor.authorKitamura Kawamoto, Fernando Yoiti [UNESP]
dc.contributor.authorTertuliano Marinho, Paulo Vinicius
dc.contributor.authorDal-Bo, Isis dos Santos
dc.contributor.authorMonteiro, Bianca Fiuza
dc.contributor.authorPrado, Leonardo
dc.contributor.authorBregadioli, Thales
dc.contributor.authorCovino Diamante, Gabriel Antonio
dc.contributor.authorAuada Ferrigno, Cassio Ricardo
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionIFSULDEMINAS
dc.date.accessioned2022-04-28T17:22:06Z
dc.date.available2022-04-28T17:22:06Z
dc.date.issued2019-09-01
dc.description.abstractAnimal models are live subjects applied to translational research. They provide insights into human diseases and enhance biomedical knowledge. Livestock production has favored the pace of human social development over millennia. Today's society is more aware of animal welfare than past generations. The general public has marked objections to animal research and many species are falling into disuse. The search for an ideal methodology to replace animal use is on, but animal modeling still holds great importance to human health. Bone research, in particular, has unmet requirements that in vitro technologies cannot yet fully address. In that sense, standardizing novel models remains necessary and rabbits are gaining in popularity as potential bone models. Our aim here is to provide a broad overview of animal modeling and its ethical implications, followed by a narrower focus on bone research and the role rabbits are playing in the current scenario.en
dc.description.affiliationUniv Sao Paulo, USP, Sch Vet Med & Anim Sci, Dept Vet Surg, Sao Paulo, SP, Brazil
dc.description.affiliationSao Paulo State Univ, UNESP, Sch Agr & Vet Sci, Dept Vet Surg, Jaboticabal, SP, Brazil
dc.description.affiliationIFSULDEMINAS, Fed Inst Educ Sci & Technol Southern Minas Gerais, Dept Vet Surg, Muzambinho, MG, Brazil
dc.description.affiliationUnespSao Paulo State Univ, UNESP, Sch Agr & Vet Sci, Dept Vet Surg, Jaboticabal, SP, Brazil
dc.format.extent162-168
dc.identifierhttp://dx.doi.org/10.1002/ame2.12083
dc.identifier.citationAnimal Models And Experimental Medicine. Hoboken: Wiley, v. 2, n. 3, p. 162-168, 2019.
dc.identifier.doi10.1002/ame2.12083
dc.identifier.issn2096-5451
dc.identifier.urihttp://hdl.handle.net/11449/218640
dc.identifier.wosWOS:000681664900003
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofAnimal Models And Experimental Medicine
dc.sourceWeb of Science
dc.subjectanimal experimentation
dc.subjectbone density
dc.subjectLagomorpha
dc.subjecttranslational medical research
dc.titleAnimal modeling in bone research-Should we follow the White Rabbit?en
dc.typeResenha
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderWiley-Blackwell
unesp.author.orcid0000-0001-9845-6126[9]
unesp.departmentClínica e Cirurgia Veterinária - FCAVpt

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Jaboticabal - FCAV - Faculdade de Ciências Agrárias e Veterinárias