Microbiological assay for ceftazidime injection

dc.contributor.authorDe Haro Moreno, Andréia [UNESP]
dc.contributor.authorSalgado, Herida Regina Nunes [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T08:47:42Z
dc.date.available2022-04-29T08:47:42Z
dc.date.issued2007-01-01
dc.description.abstractA simple, sensitive, and specific biodiffusion assay for the antibacterial ceftazidime was developed using a strain of Staphylococcus epidermidis (ATCC 12228) as the test organism. Ceftazidime was measured in powder for injection at concentrations ranging from 100 to 400 μg/mL. The calibration graph for ceftazidime was linear (r2 = 1), and the method validation showed that it was precise (relative standard deviation = 0.415) and accurate. The results obtained by biodiffusion assay were statistically calculated by linear parallel model and by means of regression analysis and were verified using analysis of variance. It was concluded that the microbiological assay is satisfactory for in vitro quantification of the antibacterial activity of ceftazidime in pharmaceuticals.en
dc.description.affiliationPrograma de Pós-Graduação em Ciências Farmacêuticas Faculdade de Ciências Farmacêuticas UNESP, Rodovia Araraquara-Jaú, km 1, CEP 14801-302, Araraquara-SP
dc.description.affiliationUnespPrograma de Pós-Graduação em Ciências Farmacêuticas Faculdade de Ciências Farmacêuticas UNESP, Rodovia Araraquara-Jaú, km 1, CEP 14801-302, Araraquara-SP
dc.format.extent1379-1382
dc.identifierhttp://dx.doi.org/10.1093/jaoac/90.5.1379
dc.identifier.citationJournal of AOAC International, v. 90, n. 5, p. 1379-1382, 2007.
dc.identifier.doi10.1093/jaoac/90.5.1379
dc.identifier.issn1060-3271
dc.identifier.scopus2-s2.0-35348886040
dc.identifier.urihttp://hdl.handle.net/11449/231817
dc.language.isoeng
dc.relation.ispartofJournal of AOAC International
dc.sourceScopus
dc.titleMicrobiological assay for ceftazidime injectionen
dc.typeArtigo
unesp.departmentFármacos e Medicamentos - FCFpt

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