Perfil cristalúrico em ovinos suplementados com cloreto de amônio
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Data
2021-10-15
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Universidade Estadual Paulista (Unesp)
Resumo
Apesar de cristais urinários serem componentes habituais, a formação de urolitíase é sempre precedida destas concreções. O estudo objetivou identificar a mudança do perfil cristalúrico em ovinos suplementados com cloreto de amônio. Foram utilizados 25 ovinos, machos, com idade de três meses, confinados e distribuídos aleatoriamente em três grupos: GRUPO GC (Controle) (n=5) não recebeu Cloreto de Amônio; GRUPO G200 (n=10) (200 mg/Kg) de Cloreto de Amônio por 56 dias consecutivos; Grupo G500 (n=10) (500 mg/Kg) de Cloreto de Amônio por 56 dias consecutivos, administrados diariamente por via oral. Os Momentos (M) de colheita de amostras e avaliação clínica foram realizados com intervalo de sete dias, sendo M0 (imediatamente antes da administração do Cloreto de Amônio), M1 (sete dias após) até M8, totalizando 70 dias de confinamento. As amostras de urina foram analisadas para se identificar a presença, o tipo e a quantidade de cristais. Houve aumento da cristalúria em todos os grupos em relação ao tempo por influência dietética, principalmente no Grupo Controle, que apresentou mais cristais de fosfato de cálcio amorfo e oxalato de cálcio. Além disso, o Grupo G500 apresentou maior presença de cristais de urato/ácido úrico após acidificação urinária, estando estes intimamente relacionados ao pH urinário.
Although urinary crystals are habitual components, urolithiasis formation is always preceded by these concretions. We aimed to identify the change in the crystalline profile in sheep supplemented with ammonium chloride. Twenty-five male sheep, aged three months, feeedlot and randomly distributed into three groups were used: CG Group (n = 5) did not receive Ammonium Chloride; G200 Group (n=10) (200 mg / kg) of Ammonium Chloride for 56 consecutive days; G500 Group (n=10) (500 mg / kg) of Ammonium Chloride for 56 consecutive days, administered daily orally. Sampling times and clinical evaluation were performed at seven days, with M0 (immediately before Ammonium Chloride), M1 (seven days after) until M8, totaling 70 days of feedlot. Urine samples were performed to identify the presence, type and quantity of crystals. There was an increase in crystalluria in all groups in relation to time due to dietary influence, mainly in the Control Group, which presented more crystals of amorphous calcium phosphate and calcium oxalate. In addition, the G500 Group presented a higher presence of urate/uric acid crystals after urinary acidification, which are closely related to urinary pH.
Although urinary crystals are habitual components, urolithiasis formation is always preceded by these concretions. We aimed to identify the change in the crystalline profile in sheep supplemented with ammonium chloride. Twenty-five male sheep, aged three months, feeedlot and randomly distributed into three groups were used: CG Group (n = 5) did not receive Ammonium Chloride; G200 Group (n=10) (200 mg / kg) of Ammonium Chloride for 56 consecutive days; G500 Group (n=10) (500 mg / kg) of Ammonium Chloride for 56 consecutive days, administered daily orally. Sampling times and clinical evaluation were performed at seven days, with M0 (immediately before Ammonium Chloride), M1 (seven days after) until M8, totaling 70 days of feedlot. Urine samples were performed to identify the presence, type and quantity of crystals. There was an increase in crystalluria in all groups in relation to time due to dietary influence, mainly in the Control Group, which presented more crystals of amorphous calcium phosphate and calcium oxalate. In addition, the G500 Group presented a higher presence of urate/uric acid crystals after urinary acidification, which are closely related to urinary pH.
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Urina análise, Sais de Amônio, Cristais, Urina, Urolitíase, Urine analysis, Ammonium's outs, Crystals, Urine, Urolithiasis