A new approach for professional dental bleaching using a polymeric catalyst primer

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dc.contributor.authorDias, Marlon Ferreira [UNESP]
dc.contributor.authorMartins, Beatriz Voss [UNESP]
dc.contributor.authorde Oliveira Ribeiro, Rafael Antonio [UNESP]
dc.contributor.authorLeite, Maria Luísa [UNESP]
dc.contributor.authorOrtecho-Zuta, Uxua [UNESP]
dc.contributor.authorHebling, Josimeri [UNESP]
dc.contributor.authorCosta, Carlos Alberto de Souza [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2023-07-29T14:32:10Z
dc.date.available2023-07-29T14:32:10Z
dc.date.issued2023-03-01
dc.description.abstractObjective: Evaluate the influence of a polymeric catalyst primer (PCP) on esthetic efficacy (EE), degradation kinetics of hydrogen peroxide (H2O2), and trans-amelodentinal cytotoxicity (TC) of bleaching gels. Materials and Methods: The following groups were established: G1: No treatment (NC, negative control); G2: PCP; G3: 10% H2O2; G4: PCP + 10% H2O2; G5: 20% H2O2; G6: PCP + 20% H2O2; G7: 35% H2O2 (positive control); G8: PCP + 35% H2O2. To determine EE, enamel/dentin discs (E/DDs) were stained and subjected or not to bleaching protocols for 45 min. To assess TC, the E/DDs were adapted to artificial pulp chambers. The extracts (culture medium + gel components diffused through E/DDs) were applied to odontoblast-like MDPC-23 cells. The viability (VB), oxidative stress (OxS), morphology (SEM), amount of H2O2 diffused and the production of hydroxyl radical (OH•) were assessed (two-way ANOVA/Tukey/paired Student t-test; p < 0.05). Results: The highest EE was found in G8 (p < 0.05), and G4, G6, and G7 did not differ statistically (p > 0.05). In G4, the limited H2O2 diffusion reduced OxS and increased cell VB (p < 0.05). Conclusions: Coating the enamel with PCP containing 10 mg/ml of manganese oxide before applying the 10% H2O2 bleaching gel maintains the EE of conventional in-office bleaching and minimizes the toxic effects of this esthetic therapy. Clinical Significance: Coating the enamel with a PCP before applying the bleaching gel may potentiate the EE of the conventional in-office tooth bleaching and reduce the toxicity of this professional therapy to the dental pulp.en
dc.description.affiliationDepartment of Dental Materials and Prosthodontics School of Dentistry São Paulo State University
dc.description.affiliationDepartment of Morphology Genetics Orthodontics and Pediatric Dentistry School of Dentistry São Paulo State University
dc.description.affiliationDepartment of Physiology and Pathology School of Dentistry São Paulo State University
dc.description.affiliationUnespDepartment of Dental Materials and Prosthodontics School of Dentistry São Paulo State University
dc.description.affiliationUnespDepartment of Morphology Genetics Orthodontics and Pediatric Dentistry School of Dentistry São Paulo State University
dc.description.affiliationUnespDepartment of Physiology and Pathology School of Dentistry São Paulo State University
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIdFAPESP: 2020/08882-6
dc.description.sponsorshipIdCNPq: 302047/2019-0
dc.description.sponsorshipIdCNPq: 408721/2018-9
dc.description.sponsorshipIdCAPES: Finance Code 001
dc.format.extent406-415
dc.identifierhttp://dx.doi.org/10.1111/jerd.12972
dc.identifier.citationJournal of Esthetic and Restorative Dentistry, v. 35, n. 2, p. 406-415, 2023.
dc.identifier.doi10.1111/jerd.12972
dc.identifier.issn1708-8240
dc.identifier.issn1496-4155
dc.identifier.scopus2-s2.0-85139149502
dc.identifier.urihttp://hdl.handle.net/11449/249222
dc.language.isoeng
dc.relation.ispartofJournal of Esthetic and Restorative Dentistry
dc.sourceScopus
dc.subjectcolor science
dc.subjectdental materials
dc.subjectodontoblasts
dc.subjecttooth bleaching
dc.subjecttoxicity
dc.titleA new approach for professional dental bleaching using a polymeric catalyst primeren
dc.typeArtigo
unesp.author.orcid0000-0001-7837-3024[1]
unesp.author.orcid0000-0002-3203-0154[2]
unesp.author.orcid0000-0001-8100-3294[3]
unesp.author.orcid0000-0001-6650-3637[4]
unesp.author.orcid0000-0002-2922-3609[5]
unesp.author.orcid0000-0002-2846-2325[6]
unesp.author.orcid0000-0002-7455-6867[7]

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