Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg

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dc.contributor.authorMarcondes, Jackson [UNESP]
dc.contributor.authorHansen, Ekkehard
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Estadual do Norte Fluminense
dc.date.accessioned2014-05-20T13:17:34Z
dc.date.available2014-05-20T13:17:34Z
dc.date.issued2008-12-01
dc.description.abstractThe obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. Transgenic lettuce seedlings were obtained through the application of a regulated balance of plant growth regulators. Genetic transformation process was acquired by cocultivation of cotyledons with Agrobacterium tumefaciens harboring the recombinant plasmid. It is the first description of a lettuce Brazilian variety Vitória de Verão genetically modified.en
dc.description.affiliationUNESP School of Agricultural Sciences and Veterinary Biochemical Laboratory of Plants and Microorganisms
dc.description.affiliationState University of North Fluminense Laboratory of Biotechnology
dc.description.affiliationUnespUNESP School of Agricultural Sciences and Veterinary Biochemical Laboratory of Plants and Microorganisms
dc.format.extent469-471
dc.identifierhttp://dx.doi.org/10.1590/S1413-86702008000600004
dc.identifier.citationBrazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 12, n. 6, p. 469-471, 2008.
dc.identifier.doi10.1590/S1413-86702008000600004
dc.identifier.fileS1413-86702008000600004.pdf
dc.identifier.issn1413-8670
dc.identifier.scieloS1413-86702008000600004
dc.identifier.urihttp://hdl.handle.net/11449/3994
dc.identifier.wosWOS:000264200300004
dc.language.isoeng
dc.publisherBrazilian Society of Infectious Diseases
dc.relation.ispartofBrazilian Journal of Infectious Diseases
dc.relation.ispartofjcr2.083
dc.relation.ispartofsjr0,817
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectEdible vaccineen
dc.subjectHepatitis Ben
dc.subjectOral immunizationen
dc.subjectRecombinant antigenen
dc.subjectTransgenic plantsen
dc.titleTransgenic lettuce seedlings carrying hepatitis B virus antigen HBsAgen
dc.typeArtigo

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