Complications with PMMA compared with other materials used in cranioplasty: a systematic review and meta-analysis

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dc.contributor.authorLeão, Rafaella de Souza
dc.contributor.authorMaior, Juliana Raposo Souto
dc.contributor.authorLemos, Cleidiel Aparecido de Araújo
dc.contributor.authorVasconcelos, Belmiro Cavalcanti do Egito [UNESP]
dc.contributor.authorMontes, Marcos Antônio Japiassú Resende
dc.contributor.authorPellizzer, Eduardo Piza
dc.contributor.authorMoraes, Sandra Lúcia Dantas
dc.contributor.institutionDentistry School
dc.contributor.institutionPrograms in Oral and Maxillofacial Surgery
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T16:54:37Z
dc.date.available2018-12-11T16:54:37Z
dc.date.issued2018-06-07
dc.description.abstractPolymethyl methacrylate (PMMA) has been considered a suitable material for cranioplasty. However, no consensus has been reached concerning the best material for cranioplasty with regard to minimizing complications. Thus, this systematic review and meta-analysis aimed to compare the complication rates of PMMA with those of autologous bone and titanium mesh. This review was registered with PROSPERO (CRD42016042725). Systematic searches were conducted on PubMed/MEDLINE, Scopus, and Web of Science. The focus question was, Do PMMA prostheses used in cranioplasty have complications rates similar to those of autologous bone and titanium mesh? A meta-analysis of complication rates was performed on the basis of dichotomous outcomes assessed by risk ratio (RR) with corresponding 95% confidence intervals (CI). From 1014 data sources, 11 articles were selected according to eligibility criteria. These articles involved 1,256 individuals and 1,278 cranioplasties using autologous bone (n = 408), PMMA (n = 379), or titanium (n = 151). The follow-up period ranged from 63 days to 54.3 months. No difference was observed between the complication rates of PMMA and autologous bone (p = 0.94; RR, 0.98; 95%CI, 0.54-1.75) or between PMMA and titanium (p = 0.38; RR, 1.59; 95%CI, 0.57-4.48). Sub-analysis of the reasons for craniotomy (trauma/non-trauma) was conducted, which revealed no significant difference (p = 0.91; RR, 0.95; 95%CI, 0.37-2.42). The meta-analysis indicated that the use of PMMA yields complication rates that are near those of autologous bone and titanium mesh.en
dc.description.affiliationUniversidade de Pernambuco - UPE Dentistry School
dc.description.affiliationUniversidade de Pernambuco - UPE Dentistry School Programs in Oral and Maxillofacial Surgery
dc.description.affiliationUniversidade Estadual Paulista - Unesp School of Dentistry Department of Dental Materials and Prosthodontics
dc.description.affiliationUnespUniversidade Estadual Paulista - Unesp School of Dentistry Department of Dental Materials and Prosthodontics
dc.format.extente31
dc.identifierhttp://dx.doi.org/10.1590/1807-3107bor-2018.vol32.0031
dc.identifier.citationBrazilian oral research, v. 32, p. e31-.
dc.identifier.doi10.1590/1807-3107bor-2018.vol32.0031
dc.identifier.fileS1806-83242018000100402.pdf
dc.identifier.issn1807-3107
dc.identifier.scieloS1806-83242018000100402
dc.identifier.scopus2-s2.0-85050430607
dc.identifier.urihttp://hdl.handle.net/11449/171255
dc.language.isoeng
dc.relation.ispartofBrazilian oral research
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.titleComplications with PMMA compared with other materials used in cranioplasty: a systematic review and meta-analysisen
dc.typeArtigo

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