Esophageal and gastric biopsies in symptomatic children and adolescents. Should both be performed?

dc.contributor.authorRodrigues, MAM
dc.contributor.authorSantos, M. E.
dc.contributor.authorMendes, E. F.
dc.contributor.authorMoreira, F. L.
dc.contributor.authorCarvalho, Mary de Assis [UNESP]
dc.contributor.authorMaffei, HVL
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:36:56Z
dc.date.available2014-05-20T13:36:56Z
dc.date.issued2004-01-01
dc.description.abstractThis study investigated the relationship among the histological diagnosis of esophagitis and gastritis in children and adolescents with gastroesophageal reflux disease (GERD) and/or dyspepsia. Records of 366 patients submitted to endoscopic biopsies were reviewed. Two groups were analyzed: G1 n=258 with esophageal and gastric biopsies, G2 n=108 with gastric biopsies only. For total subjects median age (range) was 8.5y (2mo-19.9y). Helicobacter pylori infection was detected in 30.6 %, median age 12.5y for H pylori-infected and 5.5y for uninfected children. Histological esophagitis was found in 216/258 (83.7 %) and gastritis in 95/258 (36.8 %) of G1. Both biopsies were normal for 13.6 % cases. Normal gastric biopsies were associated with esophagitis in 128/ 163 (78.5 %) of G1, but gastritis was associated with normal esophageal biopsies in only 7/95 (7.4 %) (0<.001). Histological gastritis was found in 80/108 (74.1 %) of G2 patients. Therefore, for symptomatic children both biopsies are indicated.en
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho, Dept Pathol, Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho, Dept Pathol, Botucatu, SP, Brazil
dc.format.extent15-18
dc.identifier.citationIi Intercontinental Congress of Pathology. Bologna: Medimond Publishing Co, p. 15-18, 2004.
dc.identifier.lattes1576374151262910
dc.identifier.urihttp://hdl.handle.net/11449/12723
dc.identifier.wosWOS:000225560400004
dc.language.isoeng
dc.publisherMedimond Publishing Co
dc.relation.ispartofIi Intercontinental Congress of Pathology
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titleEsophageal and gastric biopsies in symptomatic children and adolescents. Should both be performed?en
dc.typeTrabalho apresentado em evento
dcterms.rightsHolderMedimond Publishing Co
unesp.author.lattes1576374151262910
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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