Sedative and clinical effects of the pharmacopuncture with xylazine in dogs

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dc.contributor.authorCassu, Renata Navarro
dc.contributor.authorMelchert, Alessandra [UNESP]
dc.contributor.authorBignelli Canoa, Jiancarlo Tortoza
dc.contributor.authorOliveira Martins, Paula Denise de
dc.contributor.institutionUniversidade do Oeste Paulista (UNOESTE)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionAndradina Educ Fdn FEA
dc.date.accessioned2014-12-03T13:10:38Z
dc.date.available2014-12-03T13:10:38Z
dc.date.issued2014-01-01
dc.description.abstractPURPOSE: To investigate the sedative and clinical effects of the pharmacopuncture with xylazine, compared to the conventional dose of a intramuscular injection in dogs.METHODS: Twelve dogs were randomly distributed in two groups of six animals and treated as follows: control group (X-IM): 1mg kg(-1) of xylazine given intramuscularly (IM); pharmacopuncture group (X-Yintang): 0.1mg kg(-1) of xylazine diluted to 0.5 mL of saline injected into the Yin Tang acupoint. Heart rate, cardiac rhythm (ECG), systolic arterial blood pressure (SABP), respiratory rate (RR), rectal temperature (RT), blood glucose concentration, degree of sedation and adverse effects were evaluated.RESULTS: Sedative effect was observed in both groups. The degree of sedation was greater in X-IM only at 15 min when compared with X-Yintang group. Cardiovascular established was observed in X-Yintang group, while marked reduction in the HR and increased incidence of ECG abnormalities were detected in X-IM. In both treatment groups, minimal changes were observed in relation to SABP, RR, RT and blood glucose. High incidence (66%) of vomiting was observed in X-IM, while this adverse effect was absent in X-Yintang.CONCLUSION: Pharmacopuncture with xylazine induced clinically relevant sedative effects in dogs, with the advantage of reduction of undesirable side effects associated with alpha(2)-agonists, including bradycardia, cardiac arrhythmias, and emesis.en
dc.description.affiliationOeste Paulista Univ UNOESTE, Scholl Vet Med, Dept Vet Surg & Anestesiol, Presidente Prudente, SP, Brazil
dc.description.affiliationSao Paulo State Univ UNESP, Scholl Vet Med, Dept Clin Vet, Botucatu, SP, Brazil
dc.description.affiliationAndradina Educ Fdn FEA, Scholl Vet Med, Dept Vet Anestesiol, Andradina, SP, Brazil
dc.description.affiliationUniv Oeste Paulista, Scholl Vet Med, Dept Vet Surg & Anestesiol, Presidente Prudente, SP, Brazil
dc.description.affiliationUnespSao Paulo State Univ UNESP, Scholl Vet Med, Dept Clin Vet, Botucatu, SP, Brazil
dc.format.extent47-52
dc.identifierhttp://dx.doi.org/10.1590/S0102-86502014000100007
dc.identifier.citationActa Cirurgica Brasileira. São Paulo: Acta Cirurgica Brasileira, v. 29, n. 1, p. 47-52, 2014.
dc.identifier.fileS0102-86502014000100007.pdf
dc.identifier.issn0102-8650
dc.identifier.scieloS0102-86502014000100007
dc.identifier.urihttp://hdl.handle.net/11449/112336
dc.identifier.wosWOS:000330868700007
dc.language.isoeng
dc.publisherActa Cirúrgica Brasileira
dc.relation.ispartofActa Cirúrgica Brasileira
dc.relation.ispartofjcr0.933
dc.relation.ispartofsjr0,395
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectAcupunctureen
dc.subjectSedationen
dc.subjectAnxiolytic Agentsen
dc.subjectXylazineen
dc.subjectDogsen
dc.titleSedative and clinical effects of the pharmacopuncture with xylazine in dogsen
dc.typeArtigo
dcterms.rightsHolderActa Cirurgica Brasileira
unesp.author.lattes2470145375007441[2]
unesp.author.orcid0000-0003-0681-0285[1]
unesp.author.orcid0000-0002-8680-2121[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt

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Artigos - Clínica Veterinária - FMVZ