Effects of Sodium Hexametaphosphate and Fluoride on the pH and Inorganic Components of Streptococcus mutans and Candida albicans Biofilm after Sucrose Exposure

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dc.contributor.authorHosida, Thayse Yumi [UNESP]
dc.contributor.authorPessan, Juliano Pelim [UNESP]
dc.contributor.authorCavazana, Thamires Priscila [UNESP]
dc.contributor.authorSampaio, Caio [UNESP]
dc.contributor.authorde Morais, Leonardo Antônio [UNESP]
dc.contributor.authorMonteiro, Douglas Roberto [UNESP]
dc.contributor.authorDelbem, Alberto Carlos Botazzo [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversity of Western São Paulo (UNOESTE)
dc.date.accessioned2023-03-02T12:25:38Z
dc.date.available2023-03-02T12:25:38Z
dc.date.issued2022-08-01
dc.description.abstractIn order to improve the anticaries effects of fluoridated products, the supplementation of these products has been considered a promising alternative for caries control. This study evaluated the effects of sodium hexametaphosphate (HMP) and/or fluoride (F) on the inorganic components and pH of Streptococcus mutans and Candida albicans dual-species biofilms. The biofilms were treated 72, 78, and 96 h after the beginning of their formation with 0.25, 0.5, or 1% HMP-containing solutions with or without F (500 ppm, as sodium fluoride). F-containing solutions (500 ppm and 1100 ppm) and artificial saliva were used as controls. The biofilms were exposed to a 20% sucrose solution after the third treatment. Along with the biofilm pH, the concentrations of F, calcium, phosphorus (P), and HMP were determined. HMP, combined with F, increased F levels and decreased P levels in the biofilm fluid compared to that of the solution with 500 ppm F. Exposure to sucrose decreased the concentrations of all ions in the biomass, except for HMP; 1% HMP, combined with F, promoted the highest pH. It can be concluded that HMP affected the inorganic composition of the biofilm and exerted a buffering effect on the biofilm pH.en
dc.description.affiliationDepartment of Preventive and Restorative Dentistry School of Dentistry São Paulo State University (UNESP), São Paulo
dc.description.affiliationPostgraduate Program in Health Sciences University of Western São Paulo (UNOESTE), São Paulo
dc.description.affiliationUnespDepartment of Preventive and Restorative Dentistry School of Dentistry São Paulo State University (UNESP), São Paulo
dc.identifierhttp://dx.doi.org/10.3390/antibiotics11081044
dc.identifier.citationAntibiotics, v. 11, n. 8, 2022.
dc.identifier.doi10.3390/antibiotics11081044
dc.identifier.issn2079-6382
dc.identifier.scopus2-s2.0-85137377726
dc.identifier.urihttp://hdl.handle.net/11449/242250
dc.language.isoeng
dc.relation.ispartofAntibiotics
dc.sourceScopus
dc.subjectbiofilms
dc.subjectCandida albicans
dc.subjectfluorides
dc.subjecthexametaphosphate
dc.subjectHMP
dc.subjectphosphates
dc.subjectStreptococcus mutans
dc.titleEffects of Sodium Hexametaphosphate and Fluoride on the pH and Inorganic Components of Streptococcus mutans and Candida albicans Biofilm after Sucrose Exposureen
dc.typeArtigo
unesp.author.orcid0000-0002-1550-3933[2]
unesp.author.orcid0000-0003-1894-0087[5]
unesp.author.orcid0000-0001-5229-5259[6]
unesp.author.orcid0000-0002-8159-4853[7]

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