Molecular detection of albinism gene in Brazilian buffalo herds (Bubalus bubalis)

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dc.contributor.authorBernardino, Pedro N. [UNESP]
dc.contributor.authorMartins, Aline F.A. [UNESP]
dc.contributor.authorBarbosa, José D.
dc.contributor.authorSchild, Ana L.
dc.contributor.authorDamé, Maria Cecília F.
dc.contributor.authorBorges, Alexandre S. [UNESP]
dc.contributor.authorOliveira-Filho, José P. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do Pará (UFPA)
dc.contributor.institutionUniversidade Federal de Pelotas
dc.contributor.institutionEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
dc.date.accessioned2019-10-06T16:26:09Z
dc.date.available2019-10-06T16:26:09Z
dc.date.issued2019-03-01
dc.description.abstractAlbinism is a genetic disease characterized by deficient melanin production making affected animals more susceptible to skin problems, negatively influencing production systems of the same. In buffalo, a nonsense mutation (c.1431G>A) in the tyrosinase gene was already described, which is responsible for the oculocutaneous albinism buffalo phenotype. However, prevalence studies have never been performed for this anomaly in Brazil. Therefore, the objective of this study was to investigate this mutation in buffalo herd in Brazil. Of the 315 buffalo tested with no albinism phenotype evident, 11 (3.5%) were heterozygous for the mutation and none were mutated homozygous, showing the existence of the albinism gene in buffalo production herds and proving the importance of prevalence studies for hereditary diseases in order to prevent the dissemination of these same genes and their negative productivity consequences.en
dc.description.affiliationDepartamento de Clínica Veterinária Faculdade de Medicina Veterinária e Zootecnia Universidade Estadual Paulista (Unesp), Rua Prof. Doutor Walter Mauricio Correas/n, Cx. Postal 560
dc.description.affiliationInstituto de Medicina Veterinária Faculdade de Medicina Veterinária Universidade Federal do Pará (UFPA) Campus de Castanhal, Rodovia BR-316 Km 61
dc.description.affiliationLaboratório Regional de Diagnóstico Faculdade de Veterinária Universidade Federal de Pelotas, Rua Gomes Carneiro 1
dc.description.affiliationEmbrapa Clima Temperado Campus Universitário s/n
dc.description.affiliationUnespDepartamento de Clínica Veterinária Faculdade de Medicina Veterinária e Zootecnia Universidade Estadual Paulista (Unesp), Rua Prof. Doutor Walter Mauricio Correas/n, Cx. Postal 560
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIdFAPESP: 2015/23569-4
dc.description.sponsorshipIdCAPES: 432/2014
dc.format.extent175-178
dc.identifierhttp://dx.doi.org/10.1590/1678-5150-PVB-6185
dc.identifier.citationPesquisa Veterinaria Brasileira, v. 39, n. 3, p. 175-178, 2019.
dc.identifier.doi10.1590/1678-5150-PVB-6185
dc.identifier.fileS0100-736X2019000300175.pdf
dc.identifier.issn1678-5150
dc.identifier.issn0100-736X
dc.identifier.scieloS0100-736X2019000300175
dc.identifier.scopus2-s2.0-85064430934
dc.identifier.urihttp://hdl.handle.net/11449/188988
dc.language.isoeng
dc.relation.ispartofPesquisa Veterinaria Brasileira
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.titleMolecular detection of albinism gene in Brazilian buffalo herds (Bubalus bubalis)en
dc.typeArtigo
unesp.author.lattes9643433706163946[6]
unesp.author.orcid0000-0001-6256-8089[6]

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Artigos - Clínica Veterinária - FMVZ