Alterations of the gastric stump and not resected stomach mucosa after truncal vagotomy in rats

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dc.contributor.authorRodrigues, Paulo Antônio [UNESP]
dc.contributor.authorNaresse, Luiz Eduardo [UNESP]
dc.contributor.authorMinossi, José Guilherme [UNESP]
dc.contributor.authorHasimoto, Claudia Nishida
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-10-01T13:08:33Z
dc.date.available2014-10-01T13:08:33Z
dc.date.issued2014-02-01
dc.description.abstractPURPOSE:To evaluate morphological changes of the gastric stump and not resected stomach mucosa after the completion of truncal vagotomy.METHODS:Eighty male Wistar rats were divided into four groups: CT, TV, RY and RYTV. In CT group, abdominal viscera were manipulated and the abdominal cavity was closed, in TV vagal trunks were isolated and sectioned, in RY a partial Roux-en-Y gastrectomy was performed and in RYTV the vagal trunks were sectioned and a partial Roux-en-Y gastrectomy was performed. At the 54th week after surgery, the rats were euthanized. The findings were submitted to histological analyses.RESULTS:None macroscopic or histological alterations in groups TV and CT was observed. Specimens from RY and RYTV groups did not show alterations in the gastric stump mucosa. At the jejunal side of the gastroenterostomy we found shallow ulcerative lesions always single, well-defined and with variable diameter 3 to 6 mm, six times in the RY group and none in the RYTV group (RY>RYTV, p=0.008). Neoplastic or preneoplastic lesions were not diagnosed in all groups.CONCLUSION:Truncal vagotomy is a safe and non-carcinogenic method in not resected and partially resected stomach.en
dc.description.affiliationSao Paulo State University Faculty of Medicine Departament of Surgery & Orthopedics
dc.description.affiliationUNESP Faculty of Medicine Departament of Surgery & Orthopedics
dc.description.affiliationUNESP Faculty of Medicine
dc.description.affiliationUnespSao Paulo State University Faculty of Medicine Departament of Surgery & Orthopedics
dc.description.affiliationUnespUNESP Faculty of Medicine Departament of Surgery & Orthopedics
dc.description.affiliationUnespUNESP Faculty of Medicine
dc.format.extent99-103
dc.identifierhttp://dx.doi.org/10.1590/S0102-86502014000200005
dc.identifier.citationActa Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 29, n. 2, p. 99-103, 2014.
dc.identifier.doi10.1590/S0102-86502014000200005
dc.identifier.fileS0102-86502014000200099.pdf
dc.identifier.issn0102-8650
dc.identifier.lattes2755475227543451
dc.identifier.lattes3769255547738283
dc.identifier.scieloS0102-86502014000200099
dc.identifier.urihttp://hdl.handle.net/11449/109797
dc.identifier.wosWOS:000333046900005
dc.language.isoeng
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.relation.ispartofActa Cirúrgica Brasileira
dc.relation.ispartofjcr0.933
dc.relation.ispartofsjr0,395
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectVagotomy, Truncalen
dc.subjectAdenocarcinomaen
dc.subjectStomachen
dc.subjectRatsen
dc.titleAlterations of the gastric stump and not resected stomach mucosa after truncal vagotomy in ratsen
dc.typeArtigo
unesp.author.lattes2755475227543451
unesp.author.lattes3769255547738283
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentCirurgia e Ortopedia - FMBpt

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