Long-term accumulation and microdistribution of uranium in the bone and marrow of beagle dog

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dc.contributor.authorArruda-Neto, JDT
dc.contributor.authorGuevara, MVM
dc.contributor.authorNogueira, G. P.
dc.contributor.authorTaricano, I. D.
dc.contributor.authorSaiki, M.
dc.contributor.authorZamboni, C. B.
dc.contributor.authorBonamin, L. V.
dc.contributor.authorCamargo, S. P.
dc.contributor.authorCestari, A. C.
dc.contributor.authorDeppman, A.
dc.contributor.authorGarcia, F.
dc.contributor.authorGouveia, A. N.
dc.contributor.authorGuzman, F.
dc.contributor.authorHelene, OAM
dc.contributor.authorJorge, SAC
dc.contributor.authorLikhachev, V. P.
dc.contributor.authorMartins, M. N.
dc.contributor.authorMesa, J.
dc.contributor.authorRodriguez, O.
dc.contributor.authorVanin, V. R.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniv Santo Amaro
dc.contributor.institutionHigh Inst Nucl Sci & Technol
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionInstituto de Pesquisas Energéticas e Nucleares (IPEN)
dc.contributor.institutionInstituto Butantan
dc.contributor.institutionSanta Cruz State Univ
dc.date.accessioned2014-05-20T15:21:35Z
dc.date.available2014-05-20T15:21:35Z
dc.date.issued2004-08-01
dc.description.abstractThe accumulation and microdistribution of uranium in the bone and marrow of Beagle dogs were determined by both neutron activation and neutron-fission analysis. The experiment started immediately after the weaning period, lasting till maturity. Two animal groups were fed daily with uranyl nitrate at concentrations of 20 and 100 mug(-1) food. of the two measuring techniques, uranium accumulated along the marrow as much as in the bone, contrary to the results obtained with single, acute doses. The role played by this finding for the evaluation of radiobiological long-term risks is discussed. It was demonstrated, by means of a biokinetical approach, that the long-term accumulation of uranium in bone and marrow could be described by a piling up of single dose daily incorporation.en
dc.description.affiliationUniv São Paulo, Inst Phys, BR-05315970 São Paulo, Brazil
dc.description.affiliationUniv Santo Amaro, UNISA, UNITOX, Lab Toxicol Anal, São Paulo, Brazil
dc.description.affiliationHigh Inst Nucl Sci & Technol, Havana, Cuba
dc.description.affiliationUNESP, Fac Vet Med, Aracatuba, SP, Brazil
dc.description.affiliationIPEN, CNEN, Inst Energet & Nucl Res, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Inst Biol Sci, BR-05508 São Paulo, Brazil
dc.description.affiliationButanta Inst, Lab Viral Inmunol, São Paulo, Brazil
dc.description.affiliationSanta Cruz State Univ, Ilheus, BA, Brazil
dc.description.affiliationUnespUNESP, Fac Vet Med, Aracatuba, SP, Brazil
dc.format.extent567-575
dc.identifierhttp://dx.doi.org/10.1080/09553000410001723884
dc.identifier.citationInternational Journal of Radiation Biology. Abingdon: Taylor & Francis Ltd, v. 80, n. 8, p. 567-575, 2004.
dc.identifier.doi10.1080/09553000410001723884
dc.identifier.issn0955-3002
dc.identifier.urihttp://hdl.handle.net/11449/32705
dc.identifier.wosWOS:000223754400003
dc.language.isoeng
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofInternational Journal of Radiation Biology
dc.relation.ispartofjcr1.970
dc.relation.ispartofsjr0,653
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleLong-term accumulation and microdistribution of uranium in the bone and marrow of beagle dogen
dc.typeArtigo
dcterms.licensehttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dcterms.rightsHolderTaylor & Francis Ltd

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