The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol

Página do item simplificado
dc.contributor.authorBeguelini, Mateus R.
dc.contributor.authorSantiago, Cornélio S.
dc.contributor.authorGuerra, Luiz H. A. [UNESP]
dc.contributor.authorSantos, Fernanda C. A.
dc.contributor.authorGóes, Rejane M. [UNESP]
dc.contributor.authorMorielle-Versute, Eliana [UNESP]
dc.contributor.authorTaboga, Sebastião R. [UNESP]
dc.contributor.institutionUFOB - Universidade Federal Do Oeste da Bahia
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Goiás (UFG)
dc.date.accessioned2021-06-25T10:49:18Z
dc.date.available2021-06-25T10:49:18Z
dc.date.issued2021-04-01
dc.description.abstractMyotis nigricans is a species of bat from the Vespertilionidae family that is endemic of the Neotropical region. Its insectivorous feeding habit plus its large range of prey species, great geographical dispersion, wide colonies, and anthropomorphized behavior make this species an important ecological agent that acts in the control of nocturnal insects. Reproductively, M. nigricans presents geographic variations, having different patterns of reproduction according to its geographical location. Despite these extremely interesting characteristics, no more detailed study of the hormonal control of the reproduction of this species has been conducted. Therefore, the aim of the present study was to evaluate the variations in serum hormone concentrations and in uterine hormonal control of this bat during its different reproductive phases. Twenty adult females were collected, divided into four (4) sample groups, according to the reproductive status (nonreproductive, initial, and advanced pregnancy and lactating), and submitted to hormone dosage and immunohistochemical analyses. The results demonstrated that the uterus of M. nigricans is strongly regulated by the interaction/cross-talk between serum concentrations of estradiol (E2) and progesterone with their respective hormone receptors. Significant increases in the concentration of E2 and progesterone are needed to regulate the early pregnancy. The persistence of the corpus luteum throughout pregnancy is necessary, since its placenta does not express aromatase. The expressions of ERα and PR appear to be synchronized in order to coordinate a large portion of the processes that occur inside the uterus of M. nigricans during pregnancy and lactation.en
dc.description.affiliationCenter of Biological and Health Science UFOB - Universidade Federal Do Oeste da Bahia
dc.description.affiliationDepartment of Biology UNESP – University Estadual Paulista São José Do Rio Preto
dc.description.affiliationDepartment of Histology and Embryology UFG – Universidade Federal de Goiás
dc.description.affiliationDepartment of Zoology and Botany UNESP – University Estadual Paulista São José Do Rio Preto
dc.description.affiliationUnespDepartment of Biology UNESP – University Estadual Paulista São José Do Rio Preto
dc.description.affiliationUnespDepartment of Zoology and Botany UNESP – University Estadual Paulista São José Do Rio Preto
dc.format.extent211-229
dc.identifierhttp://dx.doi.org/10.1007/s00441-020-03342-2
dc.identifier.citationCell and Tissue Research, v. 384, n. 1, p. 211-229, 2021.
dc.identifier.doi10.1007/s00441-020-03342-2
dc.identifier.issn1432-0878
dc.identifier.issn0302-766X
dc.identifier.scopus2-s2.0-85099237325
dc.identifier.urihttp://hdl.handle.net/11449/207120
dc.language.isoeng
dc.relation.ispartofCell and Tissue Research
dc.sourceScopus
dc.subjectAromatase
dc.subjectEstradiol
dc.subjectProgesterone
dc.subjectUterus
dc.titleThe hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiolen
dc.typeArtigo
unesp.author.orcid0000-0002-9568-4446[1]

Arquivos

Coleções

Artigos - Biologia - IBILCE
Artigos - Zoologia e Botânica - IBILCE