Cell-mediated and humoral immunity in West syndrome

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dc.contributor.authorMontelli, T. C. B.
dc.contributor.authorIwasso, M. T. R.
dc.contributor.authorPeracoli, M. T. S.
dc.contributor.authorMota, N. G. S.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-26T18:09:00Z
dc.date.available2014-05-26T18:09:00Z
dc.date.issued1981-01-01
dc.description.abstractThe immunological status of five children with West syndrome consequent to previous cerebral lesions was investigated. Three children had West syndrome and two were in transition from West to Lennox-Gastaut syndrome. All of them showed cellular immunological deficiencies in the following tests: sensitization to DNCB, intracutaneous reaction to PHA, inhibition of leukocyte migration, blastic transformation of lymphocytes, T and B lymphocytes in peripheral blood and levels of serum immunoglobulins. These immunological deficiencies, of different degrees of severity, were associated with frequent infections in these children. A possible association between the immunological deficiencies and autoimmunity is discussed.en
dc.format.extent1-12
dc.identifierhttp://dx.doi.org/10.1590/S0004-282X1981000100001
dc.identifier.citationArquivos de Neuro-Psiquiatria, v. 39, n. 1, p. 1-12, 1981.
dc.identifier.doi10.1590/S0004-282X1981000100001
dc.identifier.file2-s2.0-0019500357.pdf
dc.identifier.issn0004-282X
dc.identifier.scieloS0004-282X1981000100001
dc.identifier.scopus2-s2.0-0019500357
dc.identifier.urihttp://hdl.handle.net/11449/63509
dc.language.isoeng
dc.relation.ispartofArquivos de Neuro-Psiquiatria
dc.relation.ispartofjcr1.015
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subject1 chloro 2,4 dinitrobenzene
dc.subjectclonazepam
dc.subjectcorticotropin
dc.subjectnitrazepam
dc.subjectphenobarbital
dc.subjectphytohemagglutinin
dc.subjectb lymphocyte
dc.subjectbrain injury
dc.subjectcellular immunity
dc.subjectcentral nervous system
dc.subjectdrug therapy
dc.subjectelectroencephalography
dc.subjectetiology
dc.subjecthumoral immunity
dc.subjectimmune deficiency
dc.subjectinfant
dc.subjectlennox gastaut syndrome
dc.subjectmajor clinical study
dc.subjectpathogenesis
dc.subjectpreschool child
dc.subjectt lymphocyte
dc.subjecttherapy
dc.subjectwest syndrome
dc.subjectAntibody Formation
dc.subjectCase Report
dc.subjectChild, Preschool
dc.subjectFemale
dc.subjectHuman
dc.subjectImmunity, Cellular
dc.subjectImmunoglobulins
dc.subjectInfant
dc.subjectLymphocyte Activation
dc.subjectMale
dc.subjectSkin Tests
dc.subjectSpasms, Infantile
dc.subjectSyndrome
dc.titleCell-mediated and humoral immunity in West syndromeen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/anp/paboutj.htm
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.departmentMicrobiologia e Imunologia - IBBpt

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