Effects of taurine on markers of muscle damage, inflammatory response and physical performance in triathletes

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dc.contributor.authorGalan, Bryan S. [UNESP]
dc.contributor.authorCarvalho, Flávia G. [UNESP]
dc.contributor.authorSantos, Priscila C. [UNESP]
dc.contributor.authorGobbi, Ronaldo B. [UNESP]
dc.contributor.authorKalva-Filho, Carlos A.
dc.contributor.authorPapoti, Marcelo
dc.contributor.authorDa Silva, Adelino S.
dc.contributor.authorFreitas, Ellen C. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2018-12-11T16:54:50Z
dc.date.available2018-12-11T16:54:50Z
dc.date.issued2018-09-01
dc.description.abstractBACKGROUND: The practice of prolonged exercise with high intensity, as seen in triathlon training, can cause physiological imbalances that might result in muscle fatigue, muscle damage and changes in systemic inflammatory response, thus reduce the athletes' physical performance, therefore, both adequate total caloric and macronutrient intake also the use of a specific ergogenic aid, as taurine supplementation would be an alternative to prevent inflammation and muscle damage. In order to verify the effects of 8 weeks of taurine and chocolate milk supplementation, markers of muscle damage, inflammation, and aerobic capacity were quantified in triathletes. METHODS: A double-blind, crossover, randomized study was conducted with 9 male long-distance triathletes, aged 25-35 years. Supplementation of 3 g of taurine (TAU) or placebo (PLA) associated with 400 mL low fat chocolate milk was performed during an 8-week period. In order to verify the effects of the supplementation protocol markers of muscle damage as lactate dehydrogenase (LDH) and creatine kinase (CK), and inflammatory markers tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) were quantified, also triathletes' performance was evaluated by exhaust test on a treadmill. RESULTS: It was observed a significant increase in taurine and CK plasma levels after TAU supplementation (P=0.02 and P=0.01, respectively). However, LDH concentrations did not differ significantly after the supplementations performed, and there were no changes in physical performance parameters; anaerobic threshold, perceived exertion, heart rate, and the concentrations of IL-6 and TNF-α. CONCLUSIONS: Taurine supplementation did not provide benefits on performance and muscle damage in triathletes.en
dc.description.affiliationFaculty of Pharmaceutical Sciences São Paulo State University (UNESP)
dc.description.affiliationInstitute of Biosciences São Paulo State University
dc.description.affiliationRibeirão Preto Medical School University of São Paulo
dc.description.affiliationSchool of Physical Education and Sport of Ribeirão Preto University of São Paulo, Avenida Bandeirantes 3900
dc.description.affiliationUnespFaculty of Pharmaceutical Sciences São Paulo State University (UNESP)
dc.description.affiliationUnespInstitute of Biosciences São Paulo State University
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdFAPESP: 2013/05620-7
dc.description.sponsorshipIdCNPq: 444579/2014-1
dc.format.extent1318-1324
dc.identifierhttp://dx.doi.org/10.23736/S0022-4707.17.07497-7
dc.identifier.citationJournal of Sports Medicine and Physical Fitness, v. 58, n. 9, p. 1318-1324, 2018.
dc.identifier.doi10.23736/S0022-4707.17.07497-7
dc.identifier.issn1827-1928
dc.identifier.issn0022-4707
dc.identifier.scopus2-s2.0-85051130280
dc.identifier.urihttp://hdl.handle.net/11449/171310
dc.language.isoeng
dc.relation.ispartofJournal of Sports Medicine and Physical Fitness
dc.relation.ispartofsjr0,477
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAthletic performance
dc.subjectChocolate
dc.subjectDietary supplements
dc.subjectTaurine
dc.titleEffects of taurine on markers of muscle damage, inflammatory response and physical performance in triathletesen
dc.typeArtigo

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