Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe

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dc.contributor.authorTrevizan, Heitor Furlan [UNESP]
dc.contributor.authorOlean-Oliveira, André [UNESP]
dc.contributor.authorCardoso, Celso Xavier [UNESP]
dc.contributor.authorTeixeira, Marcos F.S. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2021-06-25T11:17:47Z
dc.date.available2021-06-25T11:17:47Z
dc.date.issued2021-09-15
dc.description.abstractIn the present study, we report the use of an electrochemical sensor for uric acid using a molecularly imprinted polymer (MIP) as a molecular recognition platform. The MIP was based on an azopolymer electropolymerized in the presence of uric acid used as a template molecule. The azo group of the polymer contributes to the quantifiable redox capacitance of the electrode surface, which can be probed by impedance/capacitance spectroscopy. Thus, the advantage of the developed sensor is its ability to perform direct measurements without a soluble redox probe. The molecularly imprinted polymer can sensitively transduce the recognition and binding of specific analytes by redox capacitance. Through electrochemical impedance spectroscopy (EIS) and electrochemical capacitive spectroscopy (ECS), unusual approaches were able to obtain different analytical curves with distinct characteristics, reaching a limit of detection of 0.160 μmol L−1.en
dc.description.affiliationDepartment of Chemistry and Biochemistry School of Science and Technology – Sao Paulo State University (UNESP), Rua Roberto Simonsen 305
dc.description.affiliationUnespDepartment of Chemistry and Biochemistry School of Science and Technology – Sao Paulo State University (UNESP), Rua Roberto Simonsen 305
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIdFAPESP: 2016/09017-1
dc.description.sponsorshipIdCNPq: 301298/2017-3
dc.description.sponsorshipIdCAPES: 88882.434480/2019-01
dc.identifierhttp://dx.doi.org/10.1016/j.snb.2021.130141
dc.identifier.citationSensors and Actuators, B: Chemical, v. 343.
dc.identifier.doi10.1016/j.snb.2021.130141
dc.identifier.issn0925-4005
dc.identifier.scopus2-s2.0-85106476696
dc.identifier.urihttp://hdl.handle.net/11449/208712
dc.language.isoeng
dc.relation.ispartofSensors and Actuators, B: Chemical
dc.sourceScopus
dc.subjectAzopolymer
dc.subjectMolecular recognition
dc.subjectMolecularly imprinted polymer
dc.subjectResistive/capacitive sensor
dc.subjectUric acid
dc.subjectWithout redox probe
dc.titleDevelopment of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probeen
dc.typeArtigo
unesp.author.orcid0000-0002-1716-1420[2]
unesp.author.orcid0000-0002-7772-2701[3]
unesp.author.orcid0000-0001-9355-2143[4]
unesp.departmentFísica, Química e Biologia - FCTpt

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