A new scenario of bioprospecting of Hymenoptera venoms through proteomic approach

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dc.contributor.authorSantos, L. D. [UNESP]
dc.contributor.authorPieroni, M.
dc.contributor.authorMenegasso, A. R.S. [UNESP]
dc.contributor.authorPinto, J. R.A.S. [UNESP]
dc.contributor.authorPalma, M. S. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversity of Sorocaba (UNISO)
dc.date.accessioned2022-04-29T02:16:57Z
dc.date.available2022-04-29T02:16:57Z
dc.date.issued2011-01-01
dc.description.abstractVenoms represent a huge and essentially unexplored reservoir of bioactive components that may cure diseases that do not respond to currently available therapies. This review select advances reported in the literature from 2000 to the present about the new scenario of Hymenoptera venom composition. On account of new technologies in the proteomic approach, which presents high resolution and sensitivity, the combination of developments in new instruments, fragmentation methods, strategic analysis, and mass spectrometry have become indispensable tools for interrogation of protein expression, molecule interaction, and post- translational modifications. Thus, the biochemical characterization of Hymenoptera venom has become a major subject of research in the area of allergy and immunology, in which proteomics has been an excellent alternative to assist the development of more specific extracts for diagnosis and treatment of hypersensitive patients to Hymenoptera venoms. © CEVAP 2011.en
dc.description.affiliationCenter for the Study of Venoms and Venomous Animals São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo State
dc.description.affiliationUniversity of Sorocaba (UNISO), Sorocaba, São Paulo State
dc.description.affiliationCenter of Study of Social Insects Department of Biology Institute of Biosciences São Paulo State University (UNESP - Univ Estadual Paulista), Rio Claro, São Paulo State
dc.description.affiliationUnespCenter for the Study of Venoms and Venomous Animals São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo State
dc.description.affiliationUnespCenter of Study of Social Insects Department of Biology Institute of Biosciences São Paulo State University (UNESP - Univ Estadual Paulista), Rio Claro, São Paulo State
dc.format.extent364-377
dc.identifierhttp://dx.doi.org/10.1590/s1678-91992011000300004
dc.identifier.citationJournal of Venomous Animals and Toxins Including Tropical Diseases, v. 17, n. 4, p. 364-377, 2011.
dc.identifier.doi10.1590/s1678-91992011000300004
dc.identifier.issn1678-9199
dc.identifier.issn1678-9180
dc.identifier.scopus2-s2.0-83155183913
dc.identifier.urihttp://hdl.handle.net/11449/226632
dc.language.isoeng
dc.relation.ispartofJournal of Venomous Animals and Toxins Including Tropical Diseases
dc.sourceScopus
dc.subjectAllergens
dc.subjectHyaluronoglucosaminidase
dc.subjectHymenoptera
dc.subjectMass spectrometry
dc.subjectPhospholipase A1
dc.subjectProteomics
dc.subjectVenoms
dc.subjectWasp venom antigen 5
dc.titleA new scenario of bioprospecting of Hymenoptera venoms through proteomic approachen
dc.typeResenha

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Botucatu - CEVAP - Centro de Estudos de Venenos e Animais Peçonhentos
Artigos - Biologia - IBRC