Natural Polysaccharides as Active Biomaterials in Nanostructured Films for Sensing

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dc.contributor.authorEiras, Carla
dc.contributor.authorSantos, Amanda C.
dc.contributor.authorZampa, Maysa F.
dc.contributor.authorFacundo de Brito, Ana Cristina
dc.contributor.authorLeopoldo Constantino, Carlos J. [UNESP]
dc.contributor.authorZucolotto, Valtencir
dc.contributor.authordos Santos, Jose R.
dc.contributor.institutionUniversidade Federal do Piauí (UFPI)
dc.contributor.institutionIFPI
dc.contributor.institutionUniversidade Federal do Rio Grande do Norte (UFRN)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T13:23:07Z
dc.date.available2014-05-20T13:23:07Z
dc.date.issued2010-01-01
dc.description.abstractThe search for natural, biocompatible and degradable materials amenable to be used in biomedical/analytical applications has attracted attention, either from the environmental or medical point of view. Examples are the polysaccharides extracted from natural gums, which have found applications in the food and pharmaceutical industries as stabilizers or thickening agent. In a previous paper, however, it was shown that a Brazilian natural gum, chicha ( Sterculia striata), is suitable for application as building block for nanostructured film fabrication in conjunction with phthalocyanines. The films displayed electroactivity and could be used in sensing. In the present paper, we introduce the use of two different natural gums, viz., angico (Anadenanthera colubrina) and caraia (Sterculia urens), as active biomaterials to be used to modification layers, in the form of nanostructured thin films, including the study of dopamine detection. The multilayer films were assembled in conjunction with nickel tetrasulfonated phthalocyanines (NiTsPC) and displayed good chemical and electrochemical stability, allowing their use as transducer elements in sensors for detection of specific neurotransmitters. It is suggested here that nanoscale manipulation of new biodegradable natural polymers opens up a variety of new opportunities for the use of these materials in advanced biomedical and analytical devices. (C) Koninklijke Brill NV, Leiden, 2010en
dc.description.affiliationUniv Fed Piaui, CMRV, BIOTEC, Nucleo Pesquisa Biodiversidade & Biotecnol, BR-64202020 Parnaiba, PI, Brazil
dc.description.affiliationUniv Fed Piaui, CCN, Dept Quim, BR-64049550 Teresina, PI, Brazil
dc.description.affiliationIFPI, Inst Fed Educ Ciência & Tecnol Piaui, BR-64210260 Parnaiba, PI, Brazil
dc.description.affiliationUniversidade Federal do Rio Grande do Norte (UFRN), SEDIS, BR-59072970 Natal, RN, Brazil
dc.description.affiliationUNESP, FCT, DFQB, BR-19060900 Presidente Prudente, SP, Brazil
dc.description.affiliationUSP, IFSC, Grp Biofis Mol Sergio Mascarenhas, BR-13566590 São Carlos, SP, Brazil
dc.description.affiliationUnespUNESP, FCT, DFQB, BR-19060900 Presidente Prudente, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado do Piauí (FAPEPI)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIMMP/MCT
dc.format.extent1533-1543
dc.identifierhttp://dx.doi.org/10.1163/092050609X12519805626077
dc.identifier.citationJournal of Biomaterials Science-polymer Edition. Leiden: Vsp Bv, v. 21, n. 11, p. 1533-1543, 2010.
dc.identifier.doi10.1163/092050609X12519805626077
dc.identifier.issn0920-5063
dc.identifier.urihttp://hdl.handle.net/11449/6918
dc.identifier.wosWOS:000280487800008
dc.language.isoeng
dc.publisherVsp Bv
dc.relation.ispartofJournal of Biomaterials Science-polymer Edition
dc.relation.ispartofjcr1.911
dc.relation.ispartofsjr0,537
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectPolysaccharidesen
dc.subjectnanostructured filmsen
dc.subjectnanobiotechnologyen
dc.subjectdopamine detectionen
dc.titleNatural Polysaccharides as Active Biomaterials in Nanostructured Films for Sensingen
dc.typeArtigo
dcterms.licensehttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dcterms.rightsHolderVsp Bv
unesp.author.lattes6118325967319836[5]
unesp.author.orcid0000-0003-4307-3077[6]
unesp.author.orcid0000-0001-8861-774X[1]
unesp.author.orcid0000-0002-5921-3161[5]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências e Tecnologia, Presidente Prudentept
unesp.departmentFísica, Química e Biologia - FCTpt

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Presidente Prudente - FCT - Faculdade de Ciências e Tecnologia