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Antibacterial activity of a stearic acid derivative from Stemodia foliosa

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dc.contributor.authorDantas Da Silva, Lourinalda Luiza [UNESP]
dc.contributor.authorNascimento, Márcia
dc.contributor.authorSiqueira Silva, Dulce Helena [UNESP]
dc.contributor.authorFurlan, Maysa [UNESP]
dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.institutionUniversidade Federal de Pernambuco (UFPE)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:20:32Z
dc.date.available2014-05-27T11:20:32Z
dc.date.issued2002-12-01
dc.description.abstractFrom the hexane-soluble fraction of an ethanol extract from leaves and stems of Stemodia foliosa (Scrophulariaceae), the new stearic acid 4-[(n-pentoxy)phenethyl] ester (1) was isolated. This compound exhibited antibacterial properties at 10μg/mL concentration by using disc diffusion method against Gram-positive bacteria Bacillus cereus and Bacillus subtilis and fast-acid bacterium Mycobacterium fortuitum. The structure of the new compound was elucidated by spectroscopic methods and by chemical conversion.en
dc.description.affiliationDepartamento de Antibióticos Centro de Ciências Biológicas Universidade Federal de Pernambuco, PE
dc.description.affiliationNuBBE (Núcleo de Bioensaio, Biossíntese e Ecofisiologia de Produtos Naturais) Instituto de Química Universidade Estadual Paulista - UNESP, Araraquara, SP
dc.description.affiliationUnespNuBBE (Núcleo de Bioensaio, Biossíntese e Ecofisiologia de Produtos Naturais) Instituto de Química Universidade Estadual Paulista - UNESP, Araraquara, SP
dc.format.extent1137-1139
dc.identifierhttp://dx.doi.org/10.1055/s-2002-36346
dc.identifier.citationPlanta Medica, v. 68, n. 12, p. 1137-1139, 2002.
dc.identifier.doi10.1055/s-2002-36346
dc.identifier.issn0032-0943
dc.identifier.lattes1308042794786872
dc.identifier.scopus2-s2.0-0036966437
dc.identifier.urihttp://hdl.handle.net/11449/67038
dc.identifier.wosWOS:000180439100020
dc.language.isoeng
dc.relation.ispartofPlanta Medica
dc.relation.ispartofjcr2.494
dc.relation.ispartofsjr0,581
dc.rights.accessRightsAcesso restritopt
dc.sourceScopus
dc.subject4 [(n pentoxy)phenethyl] ester
dc.subjectalcohol
dc.subjectclarithromycin
dc.subjectester
dc.subjecthexane
dc.subjectplant extract
dc.subjectstearic acid derivative
dc.subjectunclassified drug
dc.subjectacid fast bacterium
dc.subjectantibacterial activity
dc.subjectBacillus subtilis
dc.subjectcontrolled study
dc.subjectGram positive bacterium
dc.subjectMycobacterium fortuitum
dc.subjectnuclear magnetic resonance spectroscopy
dc.subjectplant leaf
dc.subjectplant stem
dc.subjectScrophulariaceae
dc.subjectAnti-Bacterial Agents
dc.subjectBacteria
dc.subjectClarithromycin
dc.subjectMagnetic Resonance Spectroscopy
dc.subjectMolecular Structure
dc.subjectPlant Extracts
dc.subjectPlant Leaves
dc.subjectPlant Stems
dc.subjectStearates
dc.subjectStearic Acids
dc.subjectActinobacteria (class)
dc.subjectBacillus cereus
dc.subjectBacteria (microorganisms)
dc.subjectMycobacterium
dc.subjectPosibacteria
dc.subjectStemodia
dc.subjectuncultured actinomycete
dc.titleAntibacterial activity of a stearic acid derivative from Stemodia foliosaen
dc.typeArtigopt
dspace.entity.typePublication
relation.isDepartmentOfPublicationb3ba3d9c-022e-4521-8805-0bcceea7372e
relation.isDepartmentOfPublication.latestForDiscoveryb3ba3d9c-022e-4521-8805-0bcceea7372e
relation.isOrgUnitOfPublicationca4c0298-cd82-48ee-a9c8-c97704bac2b0
relation.isOrgUnitOfPublication.latestForDiscoveryca4c0298-cd82-48ee-a9c8-c97704bac2b0
unesp.author.lattes1308042794786872
unesp.author.orcid0000-0002-1516-7765[3]
unesp.author.orcid0000-0001-7019-5825[5]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araraquarapt
unesp.departmentFisiologia e Patologia - FOARpt

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Araraquara - FOAR - Faculdade de Odontologia