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Synthesis and antitubercular evaluation of new 1,2,3-triazole derivatives of carbohydrates

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dc.contributor.authorSantos, Juliana Alves dos
dc.contributor.authorCorrales, Roberta Cristina Novaes Reis
dc.contributor.authorPavan, Fernando Rogério [UNESP]
dc.contributor.authorLeite, Clarice Queico Fujimura [UNESP]
dc.contributor.authorDias, Rafael Mafra de Paula
dc.contributor.authorSilva, Adilson David da
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Juiz de Fora (UFJF)
dc.date.accessioned2016-01-28T16:56:19Z
dc.date.available2016-01-28T16:56:19Z
dc.date.issued2012
dc.description.abstractWe reported in this work the preparation of novel 1,4-disubstituted-1,2,3-triazoles derivatives from Dglucose and D-fructose and their in vitro antibacterial activity against Mycobacterium tuberculosis were evaluated. The chemical synthesis was performed based on the 1,3-dipolar cycloaddition reaction, and antimicrobial activity was determined based on Resazurin Microtiter Assay against Mycobacterium. None of the triazole glycoconjugates tested showed activity against these microorganisms.en
dc.description.affiliationUniversidade Federal de Juiz de Fora, Departamento de Química, Instituto de Ciências Exatas
dc.description.affiliationUnespUniversidade Estadual Paulista, Departamento de Ciências Biológicas, Faculdade de Ciências Farmacêuticas de Araraquara
dc.description.sponsorshipCoordenação de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdFAPESP: 2008/10390-2
dc.description.sponsorshipIdFAPESP: 2009/06499-1
dc.format.extent281-288
dc.identifierhttp://dx.doi.org/10.13171/mjc.1.6.2012.02.05.15
dc.identifier.citationMediterranean Journal of Chemistry, v. 1, n. 6, p. 281-288, 2012.
dc.identifier.doi10.13171/mjc.1.6.2012.02.05.15
dc.identifier.fileISSN2028-3997-2012-01-06-281-288.pdf
dc.identifier.issn2028-3997
dc.identifier.lattes9818597076971227
dc.identifier.lattes2114570774349859
dc.identifier.urihttp://hdl.handle.net/11449/133718
dc.language.isoeng
dc.relation.ispartofMediterranean Journal of Chemistry
dc.rights.accessRightsAcesso abertopt
dc.sourceCurrículo Lattes
dc.subjectCarbohydrateen
dc.subjectGlycoconjugatesen
dc.subject1,2,3-triazoleen
dc.subjectAntitubercular activityen
dc.titleSynthesis and antitubercular evaluation of new 1,2,3-triazole derivatives of carbohydratesen
dc.typeArtigopt
dspace.entity.typePublication
relation.isDepartmentOfPublication5004bcab-94af-4939-b980-091ae9d0a19e
relation.isDepartmentOfPublication.latestForDiscovery5004bcab-94af-4939-b980-091ae9d0a19e
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.author.lattes9818597076971227
unesp.author.lattes2114570774349859
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentCiências Biológicas - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas