Publicação: KINETIC-PROPERTIES OF OSSEOUS PLATE ALKALINE-PHOSPHATASE FROM DIABETIC RATS
| dc.contributor.author | Rezende, A. A. | |
| dc.contributor.author | Petenusci, S. O. | |
| dc.contributor.author | Urbinati, Elisabeth Criscuolo [UNESP] | |
| dc.contributor.author | Leone, F. A. | |
| dc.contributor.institution | Universidade de São Paulo (USP) | |
| dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
| dc.date.accessioned | 2014-05-20T15:28:18Z | |
| dc.date.available | 2014-05-20T15:28:18Z | |
| dc.date.issued | 1993-03-01 | |
| dc.description.abstract | 1. Increased levels of bone alkaline phosphatase activity were observed in diabetic rats. These animals exhibited impaired bone development without concomitant alterations of the sequence of cellular transformations.2. Alkaline phosphatase activity was delayed in diabetic rats but the kinetic parameters for the hydrolysis of p-Nitrophenylphosphate (PNPP) were virtually the same observed for controls (N = 1.2 and K0.5 = 43 muM).3. Alkaline phosphatase from diabetic rats had a better affinity (K0.5 = 38 muM) for magnesium ions than controls (K0.5 = 9 1 muM).4. Zinc ions affected alkaline phosphatase activity from control and diabetic rats in the same way (K0.5 = 10 muM). | en |
| dc.description.affiliation | UNIV SAO PAULO,FFCLRP,DEPT QUIM,BR-14040-901 RIBEIRAO PRE,SP,BRAZIL | |
| dc.description.affiliation | USP,FORP,DEPT FISIOL,SAO PAULO,BRAZIL | |
| dc.description.affiliation | UNESP,FCAVJ,DEPT MORFOL & FISIOL ANIM,SAO PAULO,BRAZIL | |
| dc.description.affiliationUnesp | UNESP,FCAVJ,DEPT MORFOL & FISIOL ANIM,SAO PAULO,BRAZIL | |
| dc.format.extent | 469-474 | |
| dc.identifier | http://dx.doi.org/10.1016/0300-9629(93)90448-D | |
| dc.identifier.citation | Comparative Biochemistry and Physiology A-physiology. Oxford: Pergamon-Elsevier B.V., v. 104, n. 3, p. 469-474, 1993. | |
| dc.identifier.doi | 10.1016/0300-9629(93)90448-D | |
| dc.identifier.issn | 0300-9629 | |
| dc.identifier.lattes | 0089991497257336 | |
| dc.identifier.uri | http://hdl.handle.net/11449/38129 | |
| dc.identifier.wos | WOS:A1993KQ76900010 | |
| dc.language.iso | eng | |
| dc.publisher | Elsevier B.V. | |
| dc.relation.ispartof | Comparative Biochemistry and Physiology A: Physiology | |
| dc.rights.accessRights | Acesso restrito | |
| dc.source | Web of Science | |
| dc.title | KINETIC-PROPERTIES OF OSSEOUS PLATE ALKALINE-PHOSPHATASE FROM DIABETIC RATS | en |
| dc.type | Artigo | |
| dcterms.license | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
| dcterms.rightsHolder | Elsevier B.V. | |
| dspace.entity.type | Publication | |
| unesp.author.lattes | 0089991497257336 | |
| unesp.author.orcid | 0000-0003-2452-4047[1] | |
| unesp.campus | Universidade Estadual Paulista (UNESP), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal | pt |
| unesp.department | Morfologia e Fisiologia Animal - FCAV | pt |
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