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On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants

dc.contributor.authorCorrea, D. R.N.
dc.contributor.authorRocha, L. A. [UNESP]
dc.contributor.authorDonato, T. A.G. [UNESP]
dc.contributor.authorSousa, K. S.J. [UNESP]
dc.contributor.authorGrandini, C. R. [UNESP]
dc.contributor.authorAfonso, C. R.M.
dc.contributor.authorDoi, H.
dc.contributor.authorTsutsumi, Y.
dc.contributor.authorHanawa, T.
dc.contributor.institutionGrupo de Pesquisa em Materiais Metálicos Avançados
dc.contributor.institutionBrazilian Branch
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.contributor.institutionTokyo Medical and Dental University
dc.contributor.institutionNational Institute for Materials Science
dc.date.accessioned2020-12-12T02:31:26Z
dc.date.available2020-12-12T02:31:26Z
dc.date.issued2020-03-01
dc.description.abstractThis study evaluated the mechanical properties and cytocompatibility of recently developed Ti-15Zr-based alloys with Mo addition for potential use as load-bearing implants. The phase composition and microstructure were changed by the alloying elements, being the β phase fully retained on the Ti-15Zr-10Mo and Ti-15Zr-15Mo samples. The TEM analysis showed that a small quantity of ω phase was precipitated on the samples with a high amount of Mo. Regarding the mechanical properties, the Ti-15Zr-10Mo sample presented high mechanical strength and large elongation (854»±»63»MPa and 18.7»±»2.8 %). However, the Ti-15Zr-15Mo sample exhibited better mechanical compatibility, due to its combination of low Young's modulus (75»±»1»GPa) and high Vickers microhardness (346»±»4»HV). Some dimple-type structures found along the fractured surface confirmed the ductile behavior of these samples. The MTT test indicated non-cytotoxic effects of all samples when in contact with osteoblastic cells (p»<»0.05). The wettability values of the samples were adequate for biomedical applications. The mechanical properties of the Ti-15Zr-15Mo sample were better than some commercial metallic biomaterials, which highlights its great potential for use as load-bearing implants.en
dc.description.affiliationIFSP Federal Institute of Education Science and Technology Grupo de Pesquisa em Materiais Metálicos Avançados
dc.description.affiliationIBTN/BR Institute of Biomaterials Tribocorrosion and Nanomedicine Brazilian Branch
dc.description.affiliationUNESP - Univ Estadual Paulista Laboratório de Anelasticidade e Biomateriais
dc.description.affiliationUFSCar - University of São Carlos Department of Materials Engineering
dc.description.affiliationInstitute of Biomaterials and Bioengineering Tokyo Medical and Dental University
dc.description.affiliationResearch Center for Structural Materials National Institute for Materials Science
dc.description.affiliationUnespUNESP - Univ Estadual Paulista Laboratório de Anelasticidade e Biomateriais
dc.format.extent1241-1250
dc.identifierhttp://dx.doi.org/10.1016/j.jmrt.2019.11.051
dc.identifier.citationJournal of Materials Research and Technology, v. 9, n. 2, p. 1241-1250, 2020.
dc.identifier.doi10.1016/j.jmrt.2019.11.051
dc.identifier.issn2238-7854
dc.identifier.scopus2-s2.0-85076520755
dc.identifier.urihttp://hdl.handle.net/11449/201396
dc.language.isoeng
dc.relation.ispartofJournal of Materials Research and Technology
dc.sourceScopus
dc.subjectBiomaterial
dc.subjectLoad-Bearing implant
dc.subjectMechanical properties
dc.subjectTi-Zr-Mo alloy
dc.titleOn the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implantsen
dc.typeArtigo
dspace.entity.typePublication
unesp.author.lattes2949983867418338[5]
unesp.author.orcid0000-0002-3336-309X[5]
unesp.departmentFísica - FCpt

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