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A novel artificial intelligence-powered tool for automated root canal segmentation in single-rooted teeth on cone-beam computed tomography

dc.contributor.authorSantos-Junior, Airton Oliveira [UNESP]
dc.contributor.authorFontenele, Rocharles Cavalcante
dc.contributor.authorNeves, Frederico Sampaio
dc.contributor.authorTanomaru-Filho, Mário [UNESP]
dc.contributor.authorJacobs, Reinhilde
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversity of Leuven
dc.contributor.institutionUniversity Hospitals Leuven
dc.contributor.institutionUniversidade Federal da Bahia (UFBA)
dc.contributor.institutionKarolinska Institutet
dc.date.accessioned2025-04-29T20:05:44Z
dc.date.issued2025-04-01
dc.description.abstractAim: To develop and validate an artificial intelligence (AI)-powered tool based on convolutional neural network (CNN) for automatic segmentation of root canals in single-rooted teeth using cone-beam computed tomography (CBCT). Methodology: A total of 69 CBCT scans were retrospectively recruited from a hospital database and acquired from two devices with varying protocols. These scans were randomly assigned to the training (n = 31, 88 teeth), validation (n = 8, 15 teeth) and testing (n = 30, 120 teeth) sets. For the training and validation data sets, each CBCT scan was imported to the Virtual Patient Creator platform, where manual segmentation of root canals was performed by two operators, establishing the ground truth. Subsequently, the AI model was tested on 30 CBCT scans (120 teeth), and the AI-generated three-dimensional (3D) virtual models were exported in standard triangle language (STL) format. Importantly, the testing data set encompassed different types of single-rooted teeth. An experienced operator evaluated the automated segmentation, and manual refinements were made to create refined 3D models (R-AI). The AI and R-AI models were compared for performance evaluation. Additionally, 30% of the testing sample was manually segmented at two different times to compare AI-based and human segmentation methods. The time taken by each segmentation method to obtain 3D models was recorded in seconds(s) for further comparison. Results: The AI-driven tool demonstrated highly accurate segmentation of single-rooted teeth (Dice similarity coefficient [DSC] ranging from 89% to 93%; 95% Hausdorff distance [HD] ranging from 0.10 to 0.13 mm), with no significant impact of tooth type on accuracy metrics (p >.05). The AI approach outperformed the manual method (p <.05), showing higher DSC and lower 95% HD values. In terms of time efficiency, manual segmentation required significantly more time (2262.4 ± 679.1 s) compared to R-AI (94 ± 64.7 s) and AI (41.8 ± 12.2 s) methods (p <.05), representing a 54-fold decrease. Conclusions: The novel AI-based tool exhibited highly accurate and time-efficient performance in the automatic root canal segmentation on CBCT, surpassing the human performance.en
dc.description.affiliationDepartment of Restorative Dentistry School of Dentistry São Paulo State University (UNESP), São Paulo
dc.description.affiliationOMFS IMPATH Research Group Department of Imaging and Pathology Faculty of Medicine University of Leuven
dc.description.affiliationDepartment of Oral and Maxillofacial Surgery University Hospitals Leuven
dc.description.affiliationDepartment of Propedeutics and Integrated Clinic Division of Oral Radiology School of Dentistry Federal University of Bahia (UFBA), Bahia
dc.description.affiliationDepartment of Dental Medicine Karolinska Institutet
dc.description.affiliationUnespDepartment of Restorative Dentistry School of Dentistry São Paulo State University (UNESP), São Paulo
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 2020/11012-3
dc.description.sponsorshipIdFAPESP: 2021/11496-3
dc.description.sponsorshipIdFAPESP: 2022/13774-3
dc.format.extent658-671
dc.identifierhttp://dx.doi.org/10.1111/iej.14200
dc.identifier.citationInternational Endodontic Journal, v. 58, n. 4, p. 658-671, 2025.
dc.identifier.doi10.1111/iej.14200
dc.identifier.issn1365-2591
dc.identifier.issn0143-2885
dc.identifier.scopus2-s2.0-86000435419
dc.identifier.urihttps://hdl.handle.net/11449/306241
dc.language.isoeng
dc.relation.ispartofInternational Endodontic Journal
dc.sourceScopus
dc.subjectartificial intelligence
dc.subjectcone-beam computed tomography
dc.subjectconvolutional neural network
dc.subjectendodontics
dc.subjectroot canal segmentation
dc.subjectsingle-rooted teeth
dc.titleA novel artificial intelligence-powered tool for automated root canal segmentation in single-rooted teeth on cone-beam computed tomographyen
dc.typeArtigopt
dspace.entity.typePublication
unesp.author.orcid0000-0003-1916-1675[1]
unesp.author.orcid0000-0002-6426-9768[2]
unesp.author.orcid0000-0001-9178-707X[3]
unesp.author.orcid0000-0002-2574-4706[4]
unesp.author.orcid0000-0002-3461-0363[5]

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