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Antimicrobial activity of endodontic sealers based on calcium hydroxide and MTA.

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The aim of this study was to evaluate the antimicrobial activity of a new root canal sealer containing calcium hydroxide (Acroseal) and the root canal sealer based on MTA (Endo CPM Sealer), in comparison with traditional sealers (Sealapex, Sealer 26 and Intrafill) and white MTA-Angelus, against five different microorganism strains. The materials and their components were evaluated after manipulation, employing the agar diffusion method. A base layer was made using Müller-Hinton agar (MH) and wells were made by removing agar. The materials were placed into the wells immediately after manipulation. The microorganisms used were: Micrococcus luteus (ATCC9341), Staphylococcus aureus (ATCC6538), Pseudomonas aeruginosa (ATCC27853), Candida albicans (ATCC 10231), and Enterococcus faecalis (ATCC 10541). The plates were kept at room temperature for 2 h for prediffusion and then incubated at 37 degrees C for 24 h. The results showed that Sealapex and its base paste, Sealer 26 and its powder, Endo CPM Sealer and its powder, white MTA and its powder all presented antimicrobial activity against all strains. Intrafill and its liquid presented antimicrobial activity against all strains except P. aeruginosa and Acroseal was effective only against M. luteus and S. aureus.

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Acroseal, aluminum derivative, antiinfective agent, bismuth, calcium derivative, calcium hydroxide, intrafill, mineral trioxide aggregate, oxide, root canal filling material, salicylic acid derivative, sealapex, Sealer 26, silicate, zinc oxide eugenol, bacterial count, Candida albicans, comparative study, drug combination, drug effect, Enterococcus faecalis, human, materials testing, Micrococcus luteus, Pseudomonas aeruginosa, Staphylococcus aureus, temperature, time, Aluminum Compounds, Anti-Infective Agents, Bismuth, Calcium Compounds, Calcium Hydroxide, Colony Count, Microbial, Drug Combinations, Humans, Materials Testing, Oxides, Root Canal Filling Materials, Salicylates, Silicates, Temperature, Time Factors, Zinc Oxide-Eugenol Cement

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Inglês

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Acta odontológica latinoamericana : AOL, v. 21, n. 2, p. 147-151, 2008.

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