Publicação: Clarifications on breakpoints in HSAX and BTAX by comparative mapping of F9, HPRT, and XIST in cattle
dc.contributor.author | Goldammer, T. | |
dc.contributor.author | Amaral, MEJ | |
dc.contributor.author | Brunner, R. M. | |
dc.contributor.author | Owens, E. | |
dc.contributor.author | Kata, SR | |
dc.contributor.author | Schwerin, M. | |
dc.contributor.author | Womack, J. E. | |
dc.contributor.institution | Res Inst Biol Farm Anim | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.contributor.institution | Texas A&M Univ | |
dc.date.accessioned | 2014-05-20T15:25:41Z | |
dc.date.available | 2014-05-20T15:25:41Z | |
dc.date.issued | 2003-01-01 | |
dc.description.abstract | The coagulation factor IX gene (179), the hypoxanthine phosphoribosyl transferase 1 gene (HPRT1), and the X-inactive specific transcript gene (XIST) were physically assigned in cattle to analyze chromosomal breakpoints on BTAX recently identified by radiation hybrid (RH) mapping experiments. Whereas the FISH assignment of XIST indicates a similar location on the q-arm of the human and cattle X chromosomes, the locus of HPRT1 supported the assumption of a chromosome rearrangement between the distal half of the q-arm of HSAX and the p-arm of BTAX identified by RH mapping. F9 previously located on the Cl-arm of BTAX was assigned to the p-arm of BTAX using RH mapping and FISH. The suggested new position of F9 close to HPRT I supports the homology between HSAXq and BTAXp. The F9 locus corresponds with the gene order found in the homologous human chromosome segment. XIST was assigned on BTAXq23, HPRT1 and F9 were mapped to BTAXp22, and the verification of the location of F9 in a 5000 rad cattle-hamster whole genome radiation hybrid panel linked the gene to markers URB10 and HPRT1. Copyright (C) 2003 S. Karger AG, Basel. | en |
dc.description.affiliation | Res Inst Biol Farm Anim, Res Unit Mol Biol, D-18196 Dummerstorf, Germany | |
dc.description.affiliation | Res Inst Biol Farm Anim, Dept Mol Biol, D-18196 Dummerstorf, Germany | |
dc.description.affiliation | UNESP, IBLICE, Dept Biol, Sao Jose Dos Campos, Brazil | |
dc.description.affiliation | Texas A&M Univ, Dept Vet Pathobiol, College Stn, TX 77843 USA | |
dc.description.affiliationUnesp | UNESP, IBLICE, Dept Biol, Sao Jose Dos Campos, Brazil | |
dc.format.extent | 39-42 | |
dc.identifier | http://dx.doi.org/10.1159/000073416 | |
dc.identifier.citation | Cytogenetic and Genome Research. Basel: Karger, v. 101, n. 1, p. 39-42, 2003. | |
dc.identifier.doi | 10.1159/000073416 | |
dc.identifier.issn | 1424-8581 | |
dc.identifier.uri | http://hdl.handle.net/11449/36053 | |
dc.identifier.wos | WOS:000186419000008 | |
dc.language.iso | eng | |
dc.publisher | Karger | |
dc.relation.ispartof | Cytogenetic and Genome Research | |
dc.relation.ispartofjcr | 1.587 | |
dc.relation.ispartofsjr | 0,748 | |
dc.rights.accessRights | Acesso restrito | pt |
dc.source | Web of Science | |
dc.title | Clarifications on breakpoints in HSAX and BTAX by comparative mapping of F9, HPRT, and XIST in cattle | en |
dc.type | Artigo | pt |
dcterms.license | http://www.karger.com/Services/RightsPermissions | |
dcterms.rightsHolder | Karger | |
dspace.entity.type | Publication | |
unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Ciência e Tecnologia, São José dos Campos | pt |
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