Publicação: Recent advancement in drug development of nitro(NO2)-heterocyclic compounds as lead scaffolds for the treatment of Mycobacterium tuberculosis
| dc.contributor.author | Scarim, Cauê Benito | |
| dc.contributor.author | Pavan, Fernando Rogério [UNESP] | |
| dc.contributor.institution | University of Mississippi Medical Center (UMMC) | |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
| dc.date.accessioned | 2022-05-01T13:41:27Z | |
| dc.date.available | 2022-05-01T13:41:27Z | |
| dc.date.issued | 2022-01-01 | |
| dc.description.abstract | Tuberculosis (TB) is an infectious disease caused predominantly by Mycobacterium tuberculosis (Mtb). It was responsible for approximately 1.4 million deaths worldwide in 2019. The lack of new drugs to treat drug-resistant strains is a principal factor for the slow rise in TB infections. Our aim is to aid the development of new TB treatments by describing improvements (last decade, 2011–2021) to nitro(NO2)-based compounds that have shown activity or pharmacological properties (e.g., anti-proliferative, anti-kinetoplastid) against Mtb. For all compounds, we have included final correlations of minimum inhibitory concentrations against Mtb (H37Rv). | en |
| dc.description.affiliation | Department of Cell and Molecular Biology University of Mississippi Medical Center (UMMC) | |
| dc.description.affiliation | School of Pharmaceutical Sciences Sao Paulo State University (UNESP), Sao Paulo | |
| dc.description.affiliationUnesp | School of Pharmaceutical Sciences Sao Paulo State University (UNESP), Sao Paulo | |
| dc.identifier | http://dx.doi.org/10.1002/ddr.21921 | |
| dc.identifier.citation | Drug Development Research. | |
| dc.identifier.doi | 10.1002/ddr.21921 | |
| dc.identifier.issn | 1098-2299 | |
| dc.identifier.issn | 0272-4391 | |
| dc.identifier.scopus | 2-s2.0-85124003111 | |
| dc.identifier.uri | http://hdl.handle.net/11449/234100 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Drug Development Research | |
| dc.source | Scopus | |
| dc.title | Recent advancement in drug development of nitro(NO2)-heterocyclic compounds as lead scaffolds for the treatment of Mycobacterium tuberculosis | en |
| dc.type | Resenha | pt |
| dspace.entity.type | Publication | |
| relation.isDepartmentOfPublication | 5004bcab-94af-4939-b980-091ae9d0a19e | |
| relation.isDepartmentOfPublication.latestForDiscovery | 5004bcab-94af-4939-b980-091ae9d0a19e | |
| unesp.author.orcid | 0000-0002-2540-6395[1] | |
| unesp.author.orcid | 0000-0002-6969-3963[2] | |
| unesp.department | Ciências Biológicas - FCF | pt |