Probiotics in the Management of Antibiotic-Associated Diarrhea in Children: A Systematic Review and Meta-analysis of Randomized and Controlled Trials
Loading...
Files
External sources
External sources
Date
Advisor
Coadvisor
Graduate program
Undergraduate course
Journal Title
Journal ISSN
Volume Title
Publisher
Type
Review
Access right
Files
External sources
External sources
Abstract
This review aimed to evaluate probiotic use to prevent antibiotic-associated diarrhea in children. A total of 1564 studies of randomized clinical trials published in English were found using PubMed, Cochrane, and Virtual Health Library (MEDLINE/LILACS). A meta-analysis included 4 trials in subgroup Lactobacillus rhamnosus (95% confidence interval [CI]: 0.17-0.49; P <.00001), 2 trials in subgroup L reuteri (95% CI: 0.51-1.77; P =.87), and 5 groups in subgroup association of species of probiotics (95% CI: 0.21-1.71; P =.33). The findings suggest that L rhamnosus alone may be useful in preventing antibiotic-associated diarrhea in children.
Description
Keywords
gastrointestinal microbiome, Lactobacillus, probiotics
Language
English
Citation
Topics in Clinical Nutrition, v. 38, n. 3, p. 211-223, 2023.
