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Dihydroisocoumarins produced by Xylaria sp and Penicillium sp., endophytic fungi associated with Piper aduncum and Alibertia macrophylla

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dc.contributor.authorOliveira, Camila M. [UNESP]
dc.contributor.authorRegasini, Luis O. [UNESP]
dc.contributor.authorSilva, Geraldo H.
dc.contributor.authorPfenning, Ludwig H.
dc.contributor.authorYoung, Maria C. M.
dc.contributor.authorBerlinck, Roberto G. S.
dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.authorAraujo, Angela R. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Sergipe (UFS)
dc.contributor.institutionUniversidade Federal de Lavras (UFLA)
dc.contributor.institutionInst Bot
dc.date.accessioned2014-05-20T14:20:04Z
dc.date.available2014-05-20T14:20:04Z
dc.date.issued2011-06-15
dc.description.abstractThe dihydroisocoumarin (3R, 4R)-3,4-dihydro-4,6-dihydroxy-3-methyl-1-oxo-1H-isochromene-5-carboxylic acid (1) was isolated from Xylaria sp., a fungus associated with Piper aduncum (Piperaceae). Additionally, two known compounds, (R)-7-hydroxymellein (2) and (3R, 4R)-4,7-dihydroxymellein (3), were isolated from Penicillium sp. associated to Alibertia macrophylla (Rubiaceae). The structures of all compounds were elucidated by analysis of spectroscopic data. The dihydrocoumarin derivatives 1-3 showed antifungal and acetylcholinesterase (AChE) inhibitory activities in vitro. (C) 2010 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.en
dc.description.affiliationUniv Estadual Paulista, NuBBE Nucleo Bioensaios Biossintese & Ecofisiol P, Inst Quim, BR-14800900 Araraquara, SP, Brazil
dc.description.affiliationUniv Fed Sergipe, Dept Quim, BR-49500000 Itabaiana, SE, Brazil
dc.description.affiliationUniversidade Federal de Lavras (UFLA), Dept Fitopatol, BR-37200000 Lavras, MG, Brazil
dc.description.affiliationInst Bot, Seccao Fisiol & Bioquim Plantas, BR-01061970 São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, NuBBE Nucleo Bioensaios Biossintese & Ecofisiol P, Inst Quim, BR-14800900 Araraquara, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipBiodiversity Virtual Institute
dc.description.sponsorshipIdBiodiversity Virtual Institute: 03/02176-7
dc.format.extent93-96
dc.identifierhttp://dx.doi.org/10.1016/j.phytol.2010.11.003
dc.identifier.citationPhytochemistry Letters. Amsterdam: Elsevier B.V., v. 4, n. 2, p. 93-96, 2011.
dc.identifier.doi10.1016/j.phytol.2010.11.003
dc.identifier.issn1874-3900
dc.identifier.orcid0000-0001-7616-9652
dc.identifier.urihttp://hdl.handle.net/11449/26027
dc.identifier.wosWOS:000290788100008
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofPhytochemistry Letters
dc.relation.ispartofjcr1.575
dc.relation.ispartofsjr0,634
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.subjectDihydroisocoumarinsen
dc.subjectEndophytic fungien
dc.subjectBioactive compoundsen
dc.titleDihydroisocoumarins produced by Xylaria sp and Penicillium sp., endophytic fungi associated with Piper aduncum and Alibertia macrophyllaen
dc.typeArtigopt
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
relation.isDepartmentOfPublicationb3ba3d9c-022e-4521-8805-0bcceea7372e
relation.isDepartmentOfPublication.latestForDiscoveryb3ba3d9c-022e-4521-8805-0bcceea7372e
relation.isOrgUnitOfPublicationca4c0298-cd82-48ee-a9c8-c97704bac2b0
relation.isOrgUnitOfPublication.latestForDiscoveryca4c0298-cd82-48ee-a9c8-c97704bac2b0
unesp.author.lattes0037579054083160[8]
unesp.author.orcid0000-0001-7616-9652[8]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araraquarapt
unesp.departmentFisiologia e Patologia - FOARpt

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Araraquara - FOAR - Faculdade de Odontologia