Publicação: Salicylic acid boosts the tio2 and zno-mediated photodegradation of paracetamol
Carregando...
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Tipo
Artigo
Direito de acesso
Resumo
Titanium dioxide (TiO2) and zinc oxide (ZnO) are among the most used catalysts in photodegradation. Paracetamol and salicylic acid are widely used as pharmaceutical drugs. We found that paracetamol is less susceptible to photodegradation compared to salicylic acid. From a chemical perspective, this was not expected since paracetamol is more vulnerable to chemical oxidation. Aiming the comprehension of this phenomenon, studies were performed comparing the efficiency of photodegradation of paracetamol versus salicylic acid and acetophenone versus 4-aminoacetophenone. The presence of amino/amide group decreased the efficiency of degradation significantly. It was also found that salicylic acid improved the degradation of paracetamol when both compounds were present in the reaction medium. The lower efficiency of photodegradation of the amino-based compounds seems to be related to the deactivation of the excited states of the TiO2 and ZnO. Theoretical calculations at the TD-PBE0/6-311++G(3df,2p) high level were performed and corroborated our proposal.
Descrição
Palavras-chave
Paracetamol, Photodegradation, Salicylic Acid, Titanium Dioxide, Zinc Oxide
Idioma
Inglês
Como citar
Materials Research, v. 24.
