Publication: Inflammatory Cytokines and BDNF Response to High-Intensity Intermittent Exercise: Effect the Exercise Volume
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Date
2016-11-04
Advisor
Coadvisor
Graduate program
Undergraduate course
Journal Title
Journal ISSN
Volume Title
Publisher
Frontiers Media Sa
Type
Article
Access right
Acesso aberto
Abstract
The purpose of this study was to compare the effects of two similar high-intensity intermittent exercises (HIIE) but different volume 1.25 km (HIIE1.25) and 2.5 km (HIIE2.5) on inflammatory and BDNF responses. Ten physically active male subjects (age 25.22 +/- 1.74 years, body mass 78.98 +/- 7.31 kg, height 1.78 +/- 0.06 m, VO2peak 59.94 9.38 ml-kg-min(-1)) performed an incremental treadmill exercise test and randomly completed two sessions of HIIE on a treadmill (1:1 min at vVO(2max) with passive recovery). Blood samples were collected at rest, immediately and 60-min after the exercise sessions. Serum was analyzed for glucose, lactate, IL-6, IL-10, and BDNF levels. Blood lactate concentrations was higher immediately post-exercise compared to rest (HIIE1.25: 1.69 0.26-7.78 +/- 2.09 mmol-L-1, and HIIE2.5: 1.89 +/- 0.26-7.38 +/- 2.57 mmol-L-1, p < 0.0001). Glucose concentrations did not present changes under the different conditions, however, levels were higher 60-min post-exercise than at rest only in the HIIE1.25 condition (rest: 76.80 +/- 11.14-97.84 +/- 24.87 mg-dL(-1), p < 0.05). BDNF level increased immediately after exercise in both protocols (HIIE1.25: 9.71 +/- 306-17.86 +/- 8.59 ng.mL(-1), and HIIE2.5: 11.83 +/- 5.82-22.84 +/- 10.30 ng.mL-1). Although both exercises increased IL-6, level percent between rest and immediately after exercise was higher in the HIIE2.5 than HIIE1.25 (30 and 10%; p = 0.014, respectively). Moreover, IL-10 levels percent increase between immediately and 60-min post exercise was higher in HIIE2.5 than HIIE1.25 (37 and 10%; p = 0.012, respectively). In conclusion, both HIIE protocols with the same intensity were effective to increase BDNF and IL-6 levels immediately after exercise while only IL-10 response was related to the durantion of exercise indicanting the importance of this exercise prescription variable.
Description
Language
English
Citation
Frontiers In Physiology. Lausanne: Frontiers Media Sa, v. 7, 8 p., 2016.
